Immunoglobulin E-mediated autoimmunity
M Maurer, S Altrichter, O Schmetzer, J Scheffel… - Frontiers in …, 2018 - frontiersin.org
The study of autoimmunity mediated by immunoglobulin E (IgE) autoantibodies, which may
be termed autoallergy, is in its infancy. It is now recognized that systemic lupus …
be termed autoallergy, is in its infancy. It is now recognized that systemic lupus …
The role of eosinophils in bullous pemphigoid: a developing model of eosinophil pathogenicity in mucocutaneous disease
Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant
mortality and morbidity. While historically BP has been characterized as an IgG driven …
mortality and morbidity. While historically BP has been characterized as an IgG driven …
Bullous pemphigoid: from the clinic to the bench
G Di Zenzo, R Della Torre, G Zambruno… - Clinics in …, 2012 - Elsevier
Bullous pemphigoid (BP) constitutes the most frequent autoimmune subepidermal blistering
disease. It is associated with autoantibodies directed against the BP antigens 180 (BP180 …
disease. It is associated with autoantibodies directed against the BP antigens 180 (BP180 …
IgG4 and IgE are the major immunoglobulins targeting the NC16A domain of BP180 in Bullous pemphigoid: serum levels of these immunoglobulins reflect disease …
R Döpp, E Schmidt, I Chimanovitch, M Leverkus… - Journal of the American …, 2000 - Elsevier
Background: Bullous pemphigoid (BP) is an autoimmune blistering disease associated with
autoantibodies against the hemidesmosomal glycoprotein BP180. The noncollagenous …
autoantibodies against the hemidesmosomal glycoprotein BP180. The noncollagenous …
Evidence for a role of eosinophils in blister formation in bullous pemphigoid
Background Bullous pemphigoid (BP) is an autoimmune bullous disease of the skin
characterized by subepidermal blister formation due to tissue‐bound and circulating …
characterized by subepidermal blister formation due to tissue‐bound and circulating …
Targeted therapies for autoimmune bullous diseases: current status
KT Amber, R Maglie, F Solimani, R Eming, M Hertl - Drugs, 2018 - Springer
Autoimmune bullous skin disorders are rare but meaningful chronic inflammatory diseases,
many of which had a poor or devastating prognosis prior to the advent of …
many of which had a poor or devastating prognosis prior to the advent of …
Correlation of IgE autoantibody to BP180 with a severe form of bullous pemphigoid
Y Iwata, K Komura, M Kodera, T Usuda… - Archives of …, 2008 - jamanetwork.com
Objective To determine the prevalence, immunoglobulin subclass distribution, and clinical
correlation of antibodies (Abs), especially of IgE Abs, to BP180 and BP230 in patients with …
correlation of antibodies (Abs), especially of IgE Abs, to BP180 and BP230 in patients with …
Mast cells are important modifiers of autoimmune disease: with so much evidence, why is there still controversy?
MA Brown, JK Hatfield - Frontiers in immunology, 2012 - frontiersin.org
There is abundant evidence that mast cells are active participants in events that mediate
tissue damage in autoimmune disease. Disease-associated increases in mast cell numbers …
tissue damage in autoimmune disease. Disease-associated increases in mast cell numbers …
IgE-mediated mechanisms in bullous pemphigoid and other autoimmune bullous diseases
N Van Beek, FS Schulze, D Zillikens… - Expert review of clinical …, 2016 - Taylor & Francis
Autoimmune bullous diseases (AIBDs) are characterized by autoantibodies against
structural proteins of the dermal–epidermal junction (in pemphigoid diseases) and the …
structural proteins of the dermal–epidermal junction (in pemphigoid diseases) and the …
Linking allergy to autoimmune disease
Type I allergy is a classical Th2-driven hypersensitivity disease based on IgE recognition of
environmental allergens. Exposure of allergic individuals to exogenous allergens leads to …
environmental allergens. Exposure of allergic individuals to exogenous allergens leads to …