Breast cancer is the second leading cause of death for women worldwide. The
heterogeneity of this disease presents a big challenge in its therapeutic management …

Breast cancer (BC) is one of the most widely diagnosed cancers and a leading cause of
cancer death among women worldwide. Globally, BC is the second most frequent cancer …

Cancer is one of the most widespread and severe diseases with a huge mortality rate. In
recent years, the second-leading mortality rate of any cancer globally has been breast …

The pathogenesis of breast cancer is driven by multiple hormones and growth factors. One
of these, prolactin (PRL), contributes to both mammary differentiation and oncogenesis, and …

Transketolase (TKT) is an enzyme that is ubiquitously expressed in all living organisms and
has been identified as an important regulator of cancer. Recent studies have shown that the …

Simple Summary The development of several antiHuman Epidermal Growth Factor
Receptor 2 (HER2) treatments over the last few years has improved the landscape of HER2 …

Breast cancer became the most diagnosed cancer in the world in 2020. Chemotherapy is
still the leading clinical strategy in breast cancer treatment, followed by hormone therapy …

The prolactin receptor (PRLR) is a member of the lactogen/cytokine receptor family, which
mediates multiple actions of prolactin (PRL). PRL is a major hormone in the proliferation …

Differences in genetic molecular features including mutation, copy number alterations and
DNA methylation, can explain interindividual variability in response to anti-cancer drugs in …

The dysregulation of gene expression is a critical event involved in all steps of
tumorigenesis. Aberrant histone and non-histone acetylation modifications of gene …