Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis

DJ Hackam, CP Sodhi - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …

Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function

MT Abreu - Nature reviews immunology, 2010 - nature.com
A single layer of epithelial cells lines the small and large intestines and functions as a barrier
between commensal bacteria and the rest of the body. Ligation of Toll-like receptors (TLRs) …

Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants

SJ Oddie, L Young, W McGuire - Cochrane database of …, 2021 - cochranelibrary.com
Background Early enteral feeding practices are potentially modifiable risk factors for
necrotising enterocolitis (NEC) in very preterm or very low birth weight (VLBW) infants …

Necrotizing enterocolitis, gut microbes, and sepsis

JW Duess, ME Sampah, CM Lopez, K Tsuboi… - Gut …, 2023 - Taylor & Francis
Necrotizing enterocolitis (NEC) is a devastating disease in premature infants and the
leading cause of death and disability from gastrointestinal disease in this vulnerable …

Using a count of neonatal morbidities to predict poor outcome in extremely low birth weight infants: added role of neonatal infection

D Bassler, BJ Stoll, B Schmidt, EV Asztalos… - …, 2009 - publications.aap.org
OBJECTIVE. A count of 3 neonatal morbidities (bronchopulmonary dysplasia, brain injury,
and severe retinopathy of prematurity) strongly predict the risk of death or neurosensory …

Necrotizing enterocolitis in the premature infant: neonatal nursing assessment, disease pathogenesis, and clinical presentation

KE Gregory, CE DeForge, KM Natale… - Advances in Neonatal …, 2011 - journals.lww.com
Necrotizing enterocolitis (NEC) remains one of the most catastrophic comorbidities
associated with prematurity. In spite of extensive research, the disease remains unsolved …

Neurodevelopmental outcomes of very low-birth-weight infants with necrotizing enterocolitis: a systematic review of observational studies

SM Schulzke, GC Deshpande… - Archives of pediatrics & …, 2007 - jamanetwork.com
Objective To systematically review observational studies reporting long-term
neurodevelopmental outcomes in very low-birth-weight neonates surviving after necrotizing …

[HTML][HTML] Current knowledge of necrotizing enterocolitis in preterm infants and the impact of different types of enteral nutrition products

J Shulhan, B Dicken, L Hartling, BMK Larsen - Advances in nutrition, 2017 - Elsevier
Preterm infants are extremely vulnerable to a range of morbidities and mortality.
Underdeveloped cardiac, respiratory, gastrointestinal, and immune systems in the preterm …

Neurodevelopment of extremely preterm infants who had necrotizing enterocolitis with or without late bacteremia

CR Martin, O Dammann, EN Allred, S Patel… - The Journal of …, 2010 - Elsevier
OBJECTIVE: To evaluate neurodevelopment after necrotizing enterocolitis (NEC) and late
bacteremia, alone and together. STUDY DESIGN: Sample included 1155 infants born at 23 …

Neurodevelopmental outcomes following necrotizing enterocolitis

M Hickey, M Georgieff, S Ramel - Seminars in Fetal and Neonatal Medicine, 2018 - Elsevier
Necrotizing enterocolitis (NEC), a gastrointestinal emergency predominantly affecting
premature infants, is associated with increased risk for poor neurodevelopmental outcomes …