Functional imaging of the lungs with gas agents

SJ Kruger, SK Nagle, MJ Couch, Y Ohno… - Journal of Magnetic …, 2016 - Wiley Online Library
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …

Quantitative imaging metrics for the assessment of pulmonary pathophysiology: an official American Thoracic Society and Fleischner Society joint workshop report

CCW Hsia, JHT Bates, B Driehuys, SB Fain… - Annals of the …, 2023 - atsjournals.org
Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Oxygen‐enhanced 3D radial ultrashort echo time magnetic resonance imaging in the healthy human lung

SJ Kruger, SB Fain, KM Johnson… - NMR in …, 2014 - Wiley Online Library
The purpose of this work was to use 3D radial ultrashort echo time (UTE) MRI to perform
whole‐lung oxygen‐enhanced (OE) imaging in humans. Eight healthy human subjects …

Validating the distribution of specific ventilation in healthy humans measured using proton MR imaging

RC Sá, AK Asadi, RJ Theilmann… - Journal of Applied …, 2014 - journals.physiology.org
Specific ventilation imaging (SVI) uses proton MRI to quantitatively map the distribution of
specific ventilation (SV) in the human lung, using inhaled oxygen as a contrast agent. To …

Phase‐cycled balanced SSFP imaging for non‐contrast‐enhanced functional lung imaging

E Ilicak, S Ozdemir, LR Schad, M Weis… - Magnetic …, 2022 - Wiley Online Library
Purpose To introduce phase‐cycled balanced SSFP (bSSFP) acquisition as an alternative in
Fourier decomposition MRI for improved robustness against field inhomogeneities. Methods …

[图书][B] The multiple inert gas elimination technique (MIGET)

SR Hopkins, PD Wagner - 2017 - Springer
The multiple inert gas elimination technique (MIGET) was born in the early 1970s in John
West's UCSD laboratory. Some 45 years later, we have thought to bring together in one …

Comparison of quantitative multiple-breath specific ventilation imaging using colocalized 2D oxygen-enhanced MRI and hyperpolarized 3He MRI

TJ Arai, FC Horn, RC Sá, MR Rao… - Journal of applied …, 2018 - journals.physiology.org
Two magnetic resonance specific ventilation imaging (SVI) techniques, namely, oxygen-
enhanced proton (OE-1H) and hyperpolarized 3He (HP-3He), were compared in eight …

Heavy upright exercise increases ventilation-perfusion mismatch in the basal lung: indirect evidence for interstitial pulmonary edema

V Tedjasaputra, RC Sá, KM Anderson… - Journal of Applied …, 2019 - journals.physiology.org
Ventilation-perfusion (V̇a/Q̇) mismatch during exercise may result from interstitial
pulmonary edema if increased pulmonary vascular pressure causes fluid efflux into the …

Regional airflow obstruction after bronchoconstriction and subsequent bronchodilation in subjects without pulmonary disease

ET Geier, RJ Theilmann, GK Prisk… - Journal of Applied …, 2019 - journals.physiology.org
Some subjects with asthma have ventilation defects that are resistant to bronchodilator
therapy, and it is thought that these resistant defects may be due to ongoing inflammation or …

Pulmonary delivery of therapeutic and diagnostic gases

WM Zapol, HC Charles, AR Martin, RC Sá… - Journal of aerosol …, 2018 - liebertpub.com
The 21st Congress for the International Society for Aerosols in Medicine included, for the first
time, a session on Pulmonary Delivery of Therapeutic and Diagnostic Gases. The rationale …