Repetitive elements in humans

T Liehr - International journal of molecular sciences, 2021 - mdpi.com
Repetitive DNA in humans is still widely considered to be meaningless, and variations within
this part of the genome are generally considered to be harmless to the carrier. In contrast, for …

Role of epigenetics in carcinogenesis: recent advancements in anticancer therapy

S Hussain, S Tulsyan, SA Dar, S Sisodiya… - Seminars in cancer …, 2022 - Elsevier
The role of epigenetics in the etiology of cancer progression is being emphasized for the
past two decades to check the impact of chromatin modifiers and remodelers. Histone …

The prognostic value and immune landscape of a cuproptosis-related lncRNA signature in head and neck squamous cell carcinoma

Y Li, H Li, Q Zhang, S Wei - Frontiers in Genetics, 2022 - frontiersin.org
Background: Cuproptosis has been recognized as a novel regulatory cell death, which has
been confirmed to promote the occurrence and development of tumors. However, whether …

Function of the long noncoding RNAs in hepatocellular carcinoma: classification, molecular mechanisms, and significant therapeutic potentials

A Khan, X Zhang - Bioengineering, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common and serious type of primary liver
cancer. HCC patients have a high death rate and poor prognosis due to the lack of clear …

[HTML][HTML] The roles of long non-coding RNAs in lung cancer

Z Cao, L Oyang, X Luo, L Xia, J Hu, J Lin, S Tan… - Journal of …, 2022 - ncbi.nlm.nih.gov
Lung cancer is the most common malignancy, being a serious threat of human lives. The
incidence and mortality of lung cancer has been increasing rapidly in the past decades …

SQLE facilitates the pancreatic cancer progression via the lncRNA‐TTN‐AS1/miR‐133b/SQLE axis

S Wang, L Dong, L Ma, S Yang, Y Zheng… - Journal of Cellular …, 2022 - Wiley Online Library
Studies have shown that SQLE is highly expressed in a variety of tumours and promotes
tumour progression. However, the role of SQLE in pancreatic cancer (PC) has not been …

The role of non-coding RNAs in the sorafenib resistance of hepatocellular carcinoma

X Hu, H Zhu, Y Shen, X Zhang, X He, X Xu - Frontiers in Oncology, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related death.
Sorafenib is approved by the US Food and Drug Administration to be a first-line …

TTN-AS1 delivered by gastric cancer cell–derived exosome induces gastric cancer progression through in vivo and in vitro studies

Y Wang, R Jiang, H Zhao, F Li, Y Li, M Zhu - Cell Biology and Toxicology, 2023 - Springer
Extracellular communication within the tumor microenvironment exerts critical functions in
tumor progression. Moreover, exosomes are capable of packaging into long non-coding …

Long non-coding RNA HEIH: a novel tumor activator in multiple cancers

J Sun, M Ni - Cancer Cell International, 2021 - Springer
The last decade has witnessed the altered expression levels of long non-coding RNA HEIH
in different types of cancer. More than half of the HEIH studies in cancer have been …

Molecular Profile of Variants in CDH1, TP53, PSCA, PRKAA1, and TTN Genes Related to Gastric Cancer Susceptibility in Amazonian Indigenous Populations

KEC Aguiar, IDS Oliveira, ADN Cohen-Paes… - Journal of Personalized …, 2023 - mdpi.com
Gastric Cancer is a disease associated with environmental and genetic changes, becoming
one of the most prevalent cancers around the world and with a high incidence in Brazil …