En route towards European clinical breakpoints for veterinary antimicrobial susceptibility testing: a position paper explaining the VetCAST approach
VetCAST is the EUCAST sub-committee for Veterinary Antimicrobial Susceptibility Testing.
Its remit is to define clinical breakpoints (CBPs) for antimicrobial drugs (AMDs) used in …
Its remit is to define clinical breakpoints (CBPs) for antimicrobial drugs (AMDs) used in …
Mathematical modeling and simulation in animal health–Part II: Principles, methods, applications, and value of physiologically based pharmacokinetic modeling in …
This review provides a tutorial for individuals interested in quantitative veterinary
pharmacology and toxicology and offers a basis for establishing guidelines for …
pharmacology and toxicology and offers a basis for establishing guidelines for …
Oral systemic bioavailability of bisphenol A and bisphenol S in pigs
V Gayrard, MZ Lacroix, FC Grandin… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: Given its hormonal activity, bisphenol S (BPS) as a substitute for bisphenol A
(BPA) could actually increase the risk of endocrine disruption if its toxicokinetic (TK) …
(BPA) could actually increase the risk of endocrine disruption if its toxicokinetic (TK) …
Pharmacokinetic–pharmacodynamic cutoff values for benzylpenicillin in horses to support the establishment of clinical breakpoints for benzylpenicillin antimicrobial …
EA Lallemand, A Bousquet-Mélou, L Chapuis… - Frontiers in …, 2023 - frontiersin.org
Introduction The aim of this international project was to establish a species-specific Clinical
Breakpoint for interpretation of Antimicrobial Susceptibility Testing of benzylpenicillin (BP) in …
Breakpoint for interpretation of Antimicrobial Susceptibility Testing of benzylpenicillin (BP) in …
Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed‐effects to characterize and quantify variability in drug pharmacokinetics
C Bon, PL Toutain, D Concordet… - Journal of veterinary …, 2018 - Wiley Online Library
A common feature of human and veterinary pharmacokinetics is the importance of
identifying and quantifying the key determinants of between‐patient variability in drug …
identifying and quantifying the key determinants of between‐patient variability in drug …
Development and application of a population physiologically based pharmacokinetic model for penicillin G in swine and cattle for food safety assessment
Penicillin G is a widely used antimicrobial in food-producing animals, and one of the most
predominant drug residues in animal-derived food products. Due to reduced sensitivity of …
predominant drug residues in animal-derived food products. Due to reduced sensitivity of …
Population pharmacokinetics/pharmacodynamics modelling of enrofloxacin for the three major trout pathogens Aeromonas salmonicida, Flavobacterium …
A Viel, A Rostang, ML Morvan, C Fournel, P Daniel… - Aquaculture, 2021 - Elsevier
Enrofloxacin is a fluoroquinolone antimicrobial agent used in freshwater rainbow trout
against the main pathogenic bacteria Aeromonas salmonicida, Yersinia ruckeri and …
against the main pathogenic bacteria Aeromonas salmonicida, Yersinia ruckeri and …
VetCAST method for determination of the pharmacokinetic-pharmacodynamic cut-off values of a long-acting formulation of florfenicol to support clinical breakpoints for …
The PK/PD cut-off (PK/PDCO) value of florfenicol for calf pathogens was determined for long
acting formulations (MSD Nuflor® and a bioequivalent generic product). PK/PDCO is one of …
acting formulations (MSD Nuflor® and a bioequivalent generic product). PK/PDCO is one of …
[HTML][HTML] Pharmacokinetics, tissue residue depletion, and withdrawal interval estimations of florfenicol in goats following repeated subcutaneous administrations
Florfenicol is a broad-spectrum antibiotic commonly used in the US to treat respiratory and
enteric infections in goats in an extra-label manner, which requires scientifically based …
enteric infections in goats in an extra-label manner, which requires scientifically based …
Integration of Food Animal Residue Avoidance Databank (FARAD) empirical methods for drug withdrawal interval determination with a mechanistic population-based …
Violative chemical residues in animal-derived food products affect food safety globally and
have impact on the trade of international agricultural products. The Food Animal Residue …
have impact on the trade of international agricultural products. The Food Animal Residue …