Pigments are widely used in the food, cosmetic, textile, pharmaceutical, and materials
industries. Demand for natural pigments has been increasing due to concerns regarding …

Highlights•Yeast synthetic biology secures valuable NP production.•Engineering yeast
enables the synthesis of new compounds with enhanced properties.•Machine learning …

Abstract (2S)-Naringenin is a key precursor for biosynthesis of various high-value flavonoids
and possesses a variety of nutritional and pharmaceutical properties on human health …

Flavones and flavonols are important classes of flavonoids with nutraceutical and
pharmacological value, and their production by fermentation with recombinant …

Flavonoids, a significant group of natural polyphenolic compounds, possess a broad
spectrum of pharmacological effects. Recent advances in the systematic metabolic …

Glucosylation is a well-known approach to improve the solubility, pharmacological, and
biological properties of flavonoids, making flavonoid glucosides a target for large-scale …

Compared with mono-O-glycosylation, di-O-glycosylation endows the precursor with better
performance. However, the mining and engineering of di-O-glycosylation patterns of …

The study aimed to evaluate the effect of digestion and gut microbiota interactions on
beetroot ketchup formulations, focusing on the release of polyphenols, bioaccessibility, and …

Microbial biofactories allow the upscaled production of high-value compounds in
biotechnological processes. This is particularly advantageous for compounds like flavonoids …

Diverse secondary metabolites in plants, with their rich biological activities, have long been
important sources for human medicine, food additives, pesticides, etc. However, the large …