Angiogenesis is an essential process in normal development and in adult physiology, but
can be disrupted in numerous diseases. The concept of targeting angiogenesis for treating …

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
adults over 50 years old. Genetic, epidemiological, and molecular studies are beginning to …

Anti-vascular endothelial growth factor (anti-VEGF) therapy currently plays a central role in
the treatment of numerous retinal diseases, most notably exudative age-related macular …

As a progressive chronic disease, age-related macular degeneration (AMD) is the leading
cause of irreversible vision impairment worldwide. Experimental and clinical evidence has …

Diseases that affect the eye, including photoreceptor degeneration, diabetic retinopathy, and
glaucoma, affect 11.8 million people in the US, resulting in vision loss and blindness. Loss of …

Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults. Vascular
pericyte degeneration is the predominant clinical manifestation of DR, yet the mechanism …

The retina, owing to its cellular anatomy and physical location, is susceptible to generating
reactive oxygen species (ROS), which are associated with several major retinal diseases …

Clinical efficacy of intravitreal anti-VEGF drugs has been widely demonstrated in several
angiogenesis-driven eye diseases including diabetic macular edema and the neovascular …

Purpose Assess short-term real-world outcomes in neovascular aged-related macular
degeneration (nAMD) treated with novel faricimab. Methods Retrospective case series of …

Purpose To evaluate the initial efficacy and safety of intravitreal faricimab in eyes previously
treated for neovascular age-related macular degeneration (nARMD). Patients and methods …