Luteolin, a flavonoid with potential for cancer prevention and therapy
Luteolin, 3', 4', 5, 7-tetrahydroxyflavone, is a common flavonoid that exists in many types of
plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been …
plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been …
Bis-and trisindolylmethanes (BIMs and TIMs)
The indole ring system is present in many natural products, pharmaceuticals,
agrochemicals, and other compounds of importance. 1–8 The indole unit forms the basis for …
agrochemicals, and other compounds of importance. 1–8 The indole unit forms the basis for …
[HTML][HTML] Indoles derived from glucobrassicin: cancer chemoprevention by indole-3-carbinol and 3, 3'-diindolylmethane
DE Williams - Frontiers in Nutrition, 2021 - frontiersin.org
Hydrolysis of glucobrassicin by plant or bacterial myrosinase produces multiple indoles
predominantly indole-3-carbinol (I3C). I3C and its major in vivo product, 3, 3' …
predominantly indole-3-carbinol (I3C). I3C and its major in vivo product, 3, 3' …
Indole-3-carbinol as a chemopreventive and anti-cancer agent
JR Weng, CH Tsai, SK Kulp, CS Chen - Cancer letters, 2008 - Elsevier
During the course of oncogenesis and tumor progression, cancer cells constitutively
upregulate signaling pathways relevant to cell proliferation and survival as a strategy to …
upregulate signaling pathways relevant to cell proliferation and survival as a strategy to …
Metastatic phenotype is regulated by estrogen in thyroid cells
S Rajoria, R Suriano, A Shanmugam, YL Wilson… - Thyroid, 2010 - liebertpub.com
Background: Over 200 million people worldwide are affected by thyroid proliferative
diseases, including cancer, adenoma, and goiter, annually. The incidences of thyroid …
diseases, including cancer, adenoma, and goiter, annually. The incidences of thyroid …
Chemopreventive properties of 3, 3′-diindolylmethane in breast cancer: evidence from experimental and human studies
CA Thomson, E Ho, MB Strom - Nutrition reviews, 2016 - academic.oup.com
Diet is a modifiable factor associated with the risk of several cancers, with convincing
evidence showing a link between diet and breast cancer. The role of bioactive compounds …
evidence showing a link between diet and breast cancer. The role of bioactive compounds …
[HTML][HTML] The epigenetic impact of cruciferous vegetables on cancer prevention
KJ Royston, TO Tollefsbol - Current pharmacology reports, 2015 - Springer
The answer to chemoprevention has perhaps been available to the general public since the
dawn of time. The epigenetic diet is of extreme interest, for research suggests that …
dawn of time. The epigenetic diet is of extreme interest, for research suggests that …
[HTML][HTML] Natural compounds as anticancer agents: Experimental evidence
J Wang, YF Jiang - World journal of experimental medicine, 2012 - ncbi.nlm.nih.gov
Cancer prevention research has drawn much attention worldwide. It is believed that some
types of cancer can be prevented by following a healthy life style. Cancer chemoprevention …
types of cancer can be prevented by following a healthy life style. Cancer chemoprevention …
[HTML][HTML] Synthetic methodologies and therapeutic potential of indole-3-carbinol (I3C) and its derivatives
F Centofanti, A Buono, M Verboni, C Tomino… - Pharmaceuticals, 2023 - mdpi.com
Indole-3-carbinol (I3C) is a natural product contained in vegetables belonging to the
Brassicaceae family and has been studied in recent decades for its biological and …
Brassicaceae family and has been studied in recent decades for its biological and …
Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells
JG Quirit, SN Lavrenov, K Poindexter, J Xu… - Biochemical …, 2017 - Elsevier
The HECT domain-containing E3 ubiquitin ligase NEDD4-1 (Neural precursor cell
Expressed Developmentally D own regulated gene 4-1) is frequently overexpressed in …
Expressed Developmentally D own regulated gene 4-1) is frequently overexpressed in …