There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …

The self-assembly of proteins is an essential process for a variety of cellular functions
including cell respiration, mobility and division. On the other hand, protein or peptide …

Adverse food reactions include immune-mediated food allergies and non-immune-mediated
intolerances. However, this distinction and the involvement of different pathogenetic …

The increase in allergy prevalence observed in recent decades may be a consequence of
early intestinal dysbiosis. The intestinal microbiota is formed in the first 1000 days of life …

B cells play a central role in the immune system through the production of antibodies. During
the past two decades, it has become increasingly clear that B cells also have the capacity to …

In the past few decades, the prevalence of allergic diseases has increased worldwide. Here,
we review the etiology and pathophysiology of allergic diseases, including the role of the …

Abstract β-Lactoglobulin (β-Lg), the main allergen of milk and dairy products, is capable of
causing food allergies in some groups, especially infants and young children. Therefore, a …

The molecular and cellular mechanisms of allergen tolerance in humans have been
intensively studied in the past few decades. The demonstration of epitope-specific T cell …

Oral antigen administration to induce regulatory T cells (Treg) takes advantage of regulatory
mechanisms that the gastrointestinal tract utilizes to promote unresponsiveness against food …

New types of protein sources will enter our diet in a near future, reinforcing the need for a
straightforward in vitro (cell‐based) screening model to test and predict the safety of these …