Chimeric antigen receptor (CAR) T-cell immunotherapy refers to an adoptive
immunotherapy that has rapidly developed in recent years. It is a novel type of treatment that …

CAR (Chimeric antigen receptor)-T cell therapy has become a very promising type of
immunotherapy against hematological cancers. This report is focused on CAR-T cells …

In recent decades, chimeric antigen receptor T (CAR-T) cell therapy has achieved dramatic
success in patients with hematological malignancies. However, CAR-T cell therapy failed to …

Chimeric antigen receptor-modified T cell therapy (CAR-T) is known to exhibit distinctive
precision, extensiveness, and persistence in anti-tumor immunity, giving rise to its …

Background Neuroblastoma is the most common extracranial solid tumor of childhood.
Patients with high-risk disease undergo extremely aggressive therapy and nonetheless …

Chimeric antigen receptors (CARs) are among the curative immunotherapeutic approaches
that exploit the antigen specificity and cytotoxicity function of potent immune cells against …

Simple Summary Neuroblastoma is a common childhood cancer with poor prognosis. Prior
studies suggest that inhibition of molecules called checkpoint proteins, which normally …

Background Based on its viral-associated or UV-associated carcinogenesis, Merkel cell
carcinoma (MCC) is a highly immunogenic skin cancer. Thus, clinically evident MCC occurs …

Based on the concept of" Evolutionary Traps", targeting survival essential genes obtained
during tumor drug resistance can effectively eliminate resistant cells. While, it still faces …

Neuroblastoma is the most common extracranial solid tumor found in childhood and is
responsible for 15% of deaths among children with cancer. Although multimodal therapies …