Free fatty acids (FFAs) have long been acknowledged for their antimicrobial activity. More
recently, long-chain FFAs (> 12 carbon atoms) are receiving increased attention for their …

The branched-chain amino acids (BCAAs [Ile, Leu, and Val]) represent important nutrients in
bacterial physiology, with roles that range from supporting protein synthesis to signaling and …

Cyclic di-adenosine monophosphate (c-di-AMP) is a broadly conserved second messenger
required for bacterial growth and infection. However, the molecular mechanisms of c-di-AMP …

The maintenance of bacterial membrane fluidity plays an important role in a variety of cell
physiological functions such as nutrient transport, protection from external adverse …

Immunity and metabolism are intimately linked; manipulating metabolism, either through diet
or genetics, has the power to alter survival during infection. However, despite metabolism's …

Fatty acids (FAs) are the major structural component of cellular membranes, which provide a
physical and chemical barrier that insulates intracellular reactions from environmental …

Methicillin-resistant Staphylococcus aureus (MRSA) infections constitute a serious health
threat worldwide, and novel antibiotics are therefore urgently needed. The enoyl-ACP …

The bacterial pathogen Listeria monocytogenes is well adapted to life in the soil and on
vegetation as a saprophyte (ie, extracellular environments) and to life in the cytosol of …

Lucinidae clams harbor gammaproteobacterial thioautotrophic gill endosymbionts that are
environmentally acquired. Thioautotrophic lucinid symbionts are related to metabolically …

The branched‐chain amino acids (BCAAs) are vital to both growth and virulence of the
human pathogen Staphylococcus aureus. In addition to supporting protein synthesis, the …