Background and Purpose—The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations in a single document for clinicians caring for adult …

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A
Guideline for Healthcare Professionals From the American Heart Association/American Stroke …

Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients
with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide …

Background and Purpose—The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations for clinicians caring for adult patients with acute …

Tenecteplase is a fibrinolytic drug with higher fibrin specificity and longer half-life than the
standard stroke thrombolytic, alteplase, permitting the convenience of single bolus …

2008 Stroke July 2017 mRS that depend, in part, on meeting or not meeting the proportional
odds assumption. 16, 18 After scientific discussion and debate in the field, investigators …

Purpose—Symptomatic intracranial hemorrhage (sICH) is the most feared complication of
intravenous thrombolytic therapy in acute ischemic stroke. Treatment of sICH is based on …

Background and Purpose—TNK (tenecteplase), a newer fibrinolytic agent, has practical
delivery advantages over ALT (alteplase) that would make it a useful agent if noninferior in …

Importance Intravenous thrombolysis with tenecteplase improves reperfusion prior to
endovascular thrombectomy for ischemic stroke compared with alteplase. Objective To …

Background and Purpose—Successful reperfusion can be achieved in more than two-thirds
of patients treated with mechanical thrombectomy. Therefore, it is important to understand …