Brain metastases affect a significant percentage of patients with advanced extracranial
malignancies. Yet, the incidence of brain metastases remains poorly described, largely due …

Brain metastases are a very common manifestation of cancer that have historically been
approached as a single disease entity given the uniform association with poor clinical …

Purpose This guideline provides updated evidence-based recommendations addressing
recent developments in the management of patients with brain metastases, including …

The number of deaths from colorectal cancer in Japan continues to increase. Colorectal
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …

PURPOSE Radiation dose to the neuroregenerative zone of the hippocampus has been
found to be associated with cognitive toxicity. Hippocampal avoidance (HA) using intensity …

An estimated 20% of all patients with cancer will develop brain metastases, with the majority
of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma …

Importance Lung cancer is the leading cause of cancer-related mortality in the United States
and worldwide. As systemic therapies improve, patients with lung cancer live longer and …

Background Whole brain radiotherapy (WBRT) and dexamethasone are widely used to treat
brain metastases from non-small cell lung cancer (NSCLC), although there have been no …

The management of patients with brain metastases has become a major issue due to the
increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014 …

Background We aimed to examine whether stereotactic radiosurgery without whole-brain
radiotherapy (WBRT) as the initial treatment for patients with five to ten brain metastases is …