Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions
MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …
been extensively researched since the landmark report by Morpurgo (1897) of “work …
[HTML][HTML] Current evidence shows no influence of women's menstrual cycle phase on acute strength performance or adaptations to resistance exercise training
LM Colenso-Semple, AC D'Souza… - Frontiers in Sports and …, 2023 - frontiersin.org
The bias towards excluding women from exercise science research is often due to the
assumption that cyclical fluctuations in reproductive hormones influence resistance exercise …
assumption that cyclical fluctuations in reproductive hormones influence resistance exercise …
Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes
RCR Meex, EE Blaak, LJC van Loon - Obesity Reviews, 2019 - Wiley Online Library
Insulin resistance and muscle mass loss often coincide in individuals with type 2 diabetes.
Most patients with type 2 diabetes are overweight, and it is well established that obesity and …
Most patients with type 2 diabetes are overweight, and it is well established that obesity and …
[HTML][HTML] Links between testosterone, oestrogen, and the growth hormone/insulin-like growth factor axis and resistance exercise muscle adaptations
N Gharahdaghi, BE Phillips, NJ Szewczyk… - Frontiers in …, 2021 - frontiersin.org
Maintenance of skeletal muscle mass throughout the life course is key for the regulation of
health, with physical activity a critical component of this, in part, due to its influence upon key …
health, with physical activity a critical component of this, in part, due to its influence upon key …
[HTML][HTML] The role of the IGF-1 signaling cascade in muscle protein synthesis and anabolic resistance in aging skeletal muscle
Sarcopenia is defined as the combined loss of skeletal muscle strength, function, and/or
mass with aging. This degenerative loss of muscle mass is associated with poor quality of …
mass with aging. This degenerative loss of muscle mass is associated with poor quality of …
[HTML][HTML] Recent advances in understanding resistance exercise training-induced skeletal muscle hypertrophy in humans
Skeletal muscle plays a pivotal role in the maintenance of physical and metabolic health
and, critically, mobility. Accordingly, strategies focused on increasing the quality and quantity …
and, critically, mobility. Accordingly, strategies focused on increasing the quality and quantity …
Training for strength and hypertrophy: an evidence-based approach
Highlights•Changes in muscle mass and strength are mediated by the FITT
principles.•Frequency: more sessions per week may mediate (volume-dependent) muscle …
principles.•Frequency: more sessions per week may mediate (volume-dependent) muscle …
[HTML][HTML] State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …
maintain, and restore healthy functioning of nearly every physiological system of the human …
[HTML][HTML] Human skeletal muscle mitochondrial adaptations following resistance exercise training
HA Parry, MD Roberts… - International journal of …, 2020 - thieme-connect.com
It is universally accepted that resistance training promotes increases in muscle strength and
hypertrophy in younger and older populations. Although less investigated, studies largely …
hypertrophy in younger and older populations. Although less investigated, studies largely …
Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men
N Gharahdaghi, S Rudrappa, MS Brook… - Journal of Cachexia …, 2019 - Wiley Online Library
Background The andropause is associated with declines in serum testosterone (T), loss of
muscle mass (sarcopenia), and frailty. Two major interventions purported to offset …
muscle mass (sarcopenia), and frailty. Two major interventions purported to offset …