Itch is a unique sensory experience that is encoded by genetically distinguishable neurons
both in the peripheral nervous system (PNS) and central nervous system (CNS) to elicit a …

Itch, in particular chronic forms, has been widely recognized as an important clinical
problem, but much less is known about the mechanisms of itch in comparison with other …

Magnetoencephalography (MEG), with its direct view to the cortex through the magnetically
transparent skull, has developed from its conception in physics laboratories to a powerful …

Chronic itch is associated with increased stress, anxiety, and other mood disorders. In turn,
stress and anxiety exacerbate itch, leading to a vicious cycle that affects patient behavior …

Unlike conventional itch, neuropathic itch develops in normal skin from excess peripheral
firing or dampened central inhibition of itch pathway neurons. Neuropathic itch is a symptom …

To be considered specific for nociception, a cortical region should:(a) have plausible
connections with ascending nociceptive pathways;(b) be activated by noxious stimuli;(c) …

Dermatologists are increasingly aware that some cases of unexplained chronic itch are
caused by underlying neurological disease, and some now seek neurological care for these …

Recent advances in pruritus research have elucidated mediators and neuronal pathways
involved in itch transmission, and this fast emerging knowledge may possibly be translated …

The itch-scratching cycle is mediated by neural dynamics in the brain. However, our
understanding of the neural dynamics during this cycle remains limited. In this study, we …

Itch is an unpleasant sensation with the desire to scratch. Although it is well known that
scratching itchy skin is pleasurable, the cerebral mechanisms underlying this phenomenon …