Inflammation is the body's response to injury and infection, involving a complex biological
response of the somatosensory, immune, autonomic, and vascular systems. Inflammatory …

Neuropathic pain has been a very active and productive clinical research field over the last
15 years. Studies have concerned multiple aspects of these complex chronic pain …

Neuropathic pain—pain caused by a lesion or disease of the somatosensory nervous
system—is underdiagnosed and difficult to treat. However, development of easy-to-use …

Pain can be induced by tissue injuries, diseases and infections. The interactions between
the peripheral nervous system (PNS) and immune system are primary actions in pain …

Objectives: This study aimed to verify these characteristics in a large UK cohort. Methods: A
cross-sectional analysis was conducted of 148,828 UK Biobank participants who completed …

Spinal cord injury (SCI) causes loss of normal sensation and often leads to debilitating
neuropathic pain (NeP). Chronic NeP develops at or below the SCI lesion in as many as …

Neuropathic pain (NP) is an increasingly common chronic pain state and a major health
burden, affecting approximately 7% to 10% of the general population. Emerging evidence …

Neuropathic pain is characterized by both sensory and affective disturbances, supporting
the notion that pain and mood disorders share common pathogenetic mechanisms …

Neuropathic pain is a chronic pain condition seen in patients with diabetic neuropathy,
cancer chemotherapy-induced neuropathy, idiopathic neuropathy as well as other diseases …

Despite the intense research on developing new therapies for neuropathic pain states,
available treatments have limited efficacy and unfavorable safety profiles. Epigenetic …