Programmed necrosis in inflammation: Toward identification of the effector molecules

D Wallach, TB Kang, CP Dillon, DR Green - Science, 2016 - science.org
BACKGROUND Inflammatory lesions often contain dead cells. Cell death in developmental
processes characteristically occurs by apoptosis, a form of programmed cell death in which …

Advanced research on vasculogenic mimicry in cancer

L Qiao, N Liang, J Zhang, J Xie, F Liu… - Journal of cellular …, 2015 - Wiley Online Library
Vasculogenic mimicry (VM) is a brand‐new tumour vascular paradigm independent of
angiogenesis that describes the specific capacity of aggressive cancer cells to form vessel …

Short linear motifs – ex nihilo evolution of protein regulation

NE Davey, MS Cyert, AM Moses - Cell Communication and Signaling, 2015 - Springer
Short sequence motifs are ubiquitous across the three major types of biomolecules:
hundreds of classes and thousands of instances of DNA regulatory elements, RNA motifs …

Subtiligase-catalyzed peptide ligation

AM Weeks, JA Wells - Chemical reviews, 2019 - ACS Publications
Subtiligase-catalyzed peptide ligation is a powerful approach for site-specific protein
bioconjugation, synthesis and semisynthesis of proteins and peptides, and chemoproteomic …

Long non-coding RNA and breast cancer

T Zhang, H Hu, G Yan, T Wu, S Liu… - … in cancer research …, 2019 - journals.sagepub.com
Breast cancer, one of the most common diseases among women, is regarded as a
heterogeneous and complicated disease that remains a major public health concern …

The DegraBase: a database of proteolysis in healthy and apoptotic human cells

ED Crawford, JE Seaman, N Agard, GW Hsu… - Molecular & Cellular …, 2013 - ASBMB
Proteolysis is a critical post-translational modification for regulation of cellular processes.
Our lab has previously developed a technique for specifically labeling unmodified protein N …

The Arabidopsis METACASPASE9 Degradome

L Tsiatsiani, E Timmerman, PJ De Bock… - The Plant …, 2013 - academic.oup.com
Metacaspases are distant relatives of the metazoan caspases, found in plants, fungi, and
protists. However, in contrast with caspases, information about the physiological substrates …

Comparative analysis of mitochondrial N-termini from mouse, human, and yeast

SE Calvo, O Julien, KR Clauser, H Shen… - Molecular & Cellular …, 2017 - ASBMB
The majority of mitochondrial proteins are encoded in the nuclear genome, translated in the
cytoplasm, and directed to the mitochondria by an N-terminal presequence that is cleaved …

Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues

JE Seaman, O Julien, PS Lee, TJ Rettenmaier… - Cell Death & …, 2016 - nature.com
Caspases are a family of proteases found in all metazoans, including a dozen in humans,
that drive the terminal stages of apoptosis as well as other cellular remodeling and …

Morphologically different hydroxyapatite nanoparticles exert differential genotoxic effects in Drosophila

M Güneş, B Yalçın, AY Burgazlı, G Tagorti… - Science of The Total …, 2023 - Elsevier
Hydroxyapatite (HAP) occurs naturally in sedimentary and metamorphic rocks and
constitutes the hard structures in many organisms. Since synthetic nano-sized HAP (HAP …