Programmed necrosis in inflammation: Toward identification of the effector molecules
BACKGROUND Inflammatory lesions often contain dead cells. Cell death in developmental
processes characteristically occurs by apoptosis, a form of programmed cell death in which …
processes characteristically occurs by apoptosis, a form of programmed cell death in which …
Advanced research on vasculogenic mimicry in cancer
Vasculogenic mimicry (VM) is a brand‐new tumour vascular paradigm independent of
angiogenesis that describes the specific capacity of aggressive cancer cells to form vessel …
angiogenesis that describes the specific capacity of aggressive cancer cells to form vessel …
Short linear motifs – ex nihilo evolution of protein regulation
Short sequence motifs are ubiquitous across the three major types of biomolecules:
hundreds of classes and thousands of instances of DNA regulatory elements, RNA motifs …
hundreds of classes and thousands of instances of DNA regulatory elements, RNA motifs …
Subtiligase-catalyzed peptide ligation
Subtiligase-catalyzed peptide ligation is a powerful approach for site-specific protein
bioconjugation, synthesis and semisynthesis of proteins and peptides, and chemoproteomic …
bioconjugation, synthesis and semisynthesis of proteins and peptides, and chemoproteomic …
Long non-coding RNA and breast cancer
T Zhang, H Hu, G Yan, T Wu, S Liu… - … in cancer research …, 2019 - journals.sagepub.com
Breast cancer, one of the most common diseases among women, is regarded as a
heterogeneous and complicated disease that remains a major public health concern …
heterogeneous and complicated disease that remains a major public health concern …
The DegraBase: a database of proteolysis in healthy and apoptotic human cells
ED Crawford, JE Seaman, N Agard, GW Hsu… - Molecular & Cellular …, 2013 - ASBMB
Proteolysis is a critical post-translational modification for regulation of cellular processes.
Our lab has previously developed a technique for specifically labeling unmodified protein N …
Our lab has previously developed a technique for specifically labeling unmodified protein N …
The Arabidopsis METACASPASE9 Degradome
L Tsiatsiani, E Timmerman, PJ De Bock… - The Plant …, 2013 - academic.oup.com
Metacaspases are distant relatives of the metazoan caspases, found in plants, fungi, and
protists. However, in contrast with caspases, information about the physiological substrates …
protists. However, in contrast with caspases, information about the physiological substrates …
Comparative analysis of mitochondrial N-termini from mouse, human, and yeast
The majority of mitochondrial proteins are encoded in the nuclear genome, translated in the
cytoplasm, and directed to the mitochondria by an N-terminal presequence that is cleaved …
cytoplasm, and directed to the mitochondria by an N-terminal presequence that is cleaved …
Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues
Caspases are a family of proteases found in all metazoans, including a dozen in humans,
that drive the terminal stages of apoptosis as well as other cellular remodeling and …
that drive the terminal stages of apoptosis as well as other cellular remodeling and …
Morphologically different hydroxyapatite nanoparticles exert differential genotoxic effects in Drosophila
Hydroxyapatite (HAP) occurs naturally in sedimentary and metamorphic rocks and
constitutes the hard structures in many organisms. Since synthetic nano-sized HAP (HAP …
constitutes the hard structures in many organisms. Since synthetic nano-sized HAP (HAP …