[HTML][HTML] Current vaccine strategies and novel approaches to combatting Francisella infection
Tularemia is caused by subspecies of Francisella tularensis and can manifest in a variety of
disease states, with the pneumonic presentation resulting in the greatest mortality. Despite …
disease states, with the pneumonic presentation resulting in the greatest mortality. Despite …
Francisella and Antibodies
K Kubelkova, A Macela - Microorganisms, 2021 - mdpi.com
Immune responses to intracellular pathogens depend largely upon the activation of T helper
type 1-dependent mechanisms. The contribution of B cells to establishing protective …
type 1-dependent mechanisms. The contribution of B cells to establishing protective …
The O-Ag antibody response to Francisella is distinct in rodents and higher animals and can serve as a correlate of protection
LE Shoudy, P Namjoshi, G Giordano, S Kumar… - Pathogens, 2021 - mdpi.com
Identifying correlates of protection (COPs) for vaccines against lethal human (Hu)
pathogens, such as Francisella tularensis (Ft), is problematic, as clinical trials are currently …
pathogens, such as Francisella tularensis (Ft), is problematic, as clinical trials are currently …
Co-Opting Host Receptors for Targeted Delivery of Bioconjugates—From Drugs to Bugs
KM Tummillo, KRO Hazlett - Molecules, 2021 - mdpi.com
Bioconjugation has allowed scientists to combine multiple functional elements into one
biological or biochemical unit. This assembly can result in the production of constructs that …
biological or biochemical unit. This assembly can result in the production of constructs that …
[图书][B] Engineering a Complement Receptor-Targeted Vaccine Platform Using Francisella tularensis as a Model
KM Tummillo - 2020 - search.proquest.com
Targeting of immunogens to be recognized by specific immune cells is a method of adjuvant-
free enhancement of vaccinations. In this work, we have targeted bacteria to complement …
free enhancement of vaccinations. In this work, we have targeted bacteria to complement …