A sensitive red/far-red photoswitch for controllable gene therapy in mouse models of metabolic diseases
L Qiao, L Niu, M Wang, Z Wang, D Kong, G Yu… - Nature …, 2024 - nature.com
Red light optogenetic systems are in high demand for the precise control of gene expression
for gene-and cell-based therapies. Here, we report a red/far-red l ight-i nducible p …
for gene-and cell-based therapies. Here, we report a red/far-red l ight-i nducible p …
Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution
The glucagon-like peptide-1 receptor (GLP1R) is a broadly expressed target of peptide
hormones with essential roles in energy and glucose homeostasis, as well as of the …
hormones with essential roles in energy and glucose homeostasis, as well as of the …
Optogenetics in pancreatic islets: Actuators and effects
CG Gangemi, H Janovjak - Diabetes, 2024 - diabetesjournals.org
The islets of Langerhans reside within the endocrine pancreas as highly vascularized
microorgans that are responsible for the secretion of key hormones, such as insulin and …
microorgans that are responsible for the secretion of key hormones, such as insulin and …
Plant sources containing berberine with potential of control type 2 diabetes mellitus: A brief literature review
S Shiri, K Gharanjig, H Heidari, A Tahghighi - Functional Food Science …, 2024 - ffhdj.com
Berberine (BBR) is a bioactive compound found in some plants. Plants containing BBR are
used as important functional food supplements, particularly for their potent oral …
used as important functional food supplements, particularly for their potent oral …
Light-Mediated Enhancement of Glucose-Stimulated Insulin Release of Optogenetically Engineered Human Pancreatic Beta-Cells
Z Chen, DM Stoukides, ES Tzanakakis - ACS Synthetic Biology, 2024 - ACS Publications
Enhancement of glucose-stimulated insulin secretion (GSIS) in exogenously delivered
pancreatic β-cells is desirable, for example, to overcome the insulin resistance manifested in …
pancreatic β-cells is desirable, for example, to overcome the insulin resistance manifested in …