Mechanics of 3D cell–hydrogel interactions: experiments, models, and mechanisms
Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
Computational modelling of cell spreading and tissue regeneration in porous scaffolds
Improved biological and mechanical functionality of musculoskeletal tissue-engineered
constructs is required for clinical application, which can only be achieved by comprehensive …
constructs is required for clinical application, which can only be achieved by comprehensive …
Biodendrimer-based hydrogel scaffolds for cartilage tissue repair
SHM Söntjens, DL Nettles, MA Carnahan… - …, 2006 - ACS Publications
Photo-crosslinkable dendritic macromolecules are attractive materials for the preparation of
cartilage tissue engineering scaffolds that may be optimized for in situ formation of hydrated …
cartilage tissue engineering scaffolds that may be optimized for in situ formation of hydrated …
EDC/NHS-crosslinked type II collagen-chondroitin sulfate scaffold: characterization and in vitro evaluation
H Cao, SY Xu - Journal of Materials Science: Materials in Medicine, 2008 - Springer
Three-dimensional biodegradable porous type II collagen scaffolds are interesting materials
for cartilage tissue engineering. This study reports the preparation of porous type II collagen …
for cartilage tissue engineering. This study reports the preparation of porous type II collagen …
Tuning tissue growth with scaffold degradation in enzyme-sensitive hydrogels: a mathematical model
Despite tremendous advances in the field of tissue engineering, a number of obstacles
remain that hinder its successful translation to the clinic. One challenge that relates to the …
remain that hinder its successful translation to the clinic. One challenge that relates to the …
Comparison of patient-specific computational models vs. clinical follow-up, for adjacent segment disc degeneration and bone remodelling after spinal fusion
M Rijsbergen, B van Rietbergen, V Barthelemy… - PLoS …, 2018 - journals.plos.org
Spinal fusion is a standard surgical treatment for patients suffering from low back pain
attributed to disc degeneration. However, results are somewhat variable and unpredictable …
attributed to disc degeneration. However, results are somewhat variable and unpredictable …
Poly (lactide-co-glycolide) microspheres as a moldable scaffold for cartilage tissue engineering
NR Mercier, HR Costantino, MA Tracy, LJ Bonassar - Biomaterials, 2005 - Elsevier
This study demonstrates the use of biodegradable poly (lactide-co-glycolide)(PLG)
microspheres as a moldable scaffold for cartilage tissue engineering. Chondrocytes were …
microspheres as a moldable scaffold for cartilage tissue engineering. Chondrocytes were …
Heterogeneity is key to hydrogel-based cartilage tissue regeneration
SL Sridhar, MC Schneider, S Chu, G De Roucy… - Soft Matter, 2017 - pubs.rsc.org
Degradable hydrogels have been developed to provide initial mechanical support to
encapsulated cells while facilitating the growth of neo-tissues. When cells are encapsulated …
encapsulated cells while facilitating the growth of neo-tissues. When cells are encapsulated …
Enabling tools for engineering collagenous tissues integrating bioreactors, intravital imaging, and biomechanical modeling
Many investigators have engineered diverse connective tissues having good mechanical
properties, yet few tools enable a global understanding of the associated formation of …
properties, yet few tools enable a global understanding of the associated formation of …
Nanostructured injectable cell microcarriers for tissue regeneration
Z Zhang, TW Eyster, PX Ma - Nanomedicine, 2016 - Taylor & Francis
Biodegradable polymer microspheres have emerged as cell carriers for the regeneration
and repair of irregularly shaped tissue defects due to their injectability, controllable …
and repair of irregularly shaped tissue defects due to their injectability, controllable …