The magic of bicelles lights up membrane protein structure

UHN Dürr, M Gildenberg, A Ramamoorthy - Chemical reviews, 2012 - ACS Publications
Biological membranes and membrane proteins, responsible for numerous exciting
biological processes, present one of the paramount challenges in biophysics today …

When detergent meets bilayer: birth and coming of age of lipid bicelles

UHN Dürr, R Soong, A Ramamoorthy - Progress in nuclear magnetic …, 2013 - Elsevier
► Lipid bicelles have matured to full membership in the club of lipid phases.► Numerous
techniques have elucidated the character traits of bicelles.► Bicelles are exemplary citizens …

Three-dimensional structure of the transmembrane domain of Vpu from HIV-1 in aligned phospholipid bicelles

SH Park, AA De Angelis, AA Nevzorov, CH Wu… - Biophysical journal, 2006 - cell.com
The three-dimensional backbone structure of the transmembrane domain of Vpu from HIV-1
was determined by solid-state NMR spectroscopy in two magnetically-aligned phospholipid …

On the role of NMR spectroscopy for characterization of antimicrobial peptides

F Porcelli, A Ramamoorthy, G Barany… - … : Folding, Association, and …, 2013 - Springer
Antimicrobial peptides (AMPs) provide a primordial source of immunity, conferring upon
eukaryotic cells resistance against bacteria, protozoa, and viruses. Despite a few examples …

Membrane disruption mechanism of a prion peptide (106–126) investigated by atomic force microscopy, Raman and electron paramagnetic resonance spectroscopy

J Pan, PK Sahoo, A Dalzini, Z Hayati… - The Journal of …, 2017 - ACS Publications
A fragment of the human prion protein spanning residues 106–126 (PrP106–126)
recapitulates many essential properties of the disease-causing protein such as …

[HTML][HTML] Alamethicin in bicelles: orientation, aggregation, and bilayer modification as a function of peptide concentration

M Bortolus, M De Zotti, F Formaggio… - Biochimica et Biophysica …, 2013 - Elsevier
Alamethicin is a 19-amino-acid residue hydrophobic peptide of the peptaibol family that has
been the object of numerous studies for its ability to produce voltage-dependent ion …

Temperature driven annealing of perforations in bicellar model membranes

MP Nieh, VA Raghunathan, G Pabst, T Harroun… - Langmuir, 2011 - ACS Publications
Bicellar model membranes composed of 1, 2-dimyristoylphosphatidylcholine (DMPC) and 1,
2-dihexanoylphosphatidylcholine (DHPC), with a DMPC/DHPC molar ratio of 5, and doped …

The influence of static magnetic fields on mechanosensitive ion channel activity in artificial liposomes

S Hughes, AJ El Haj, J Dobson, B Martinac - European Biophysics Journal, 2005 - Springer
The influence of static magnetic fields (SMFs) on the activity of recombinant
mechanosensitive ion channels (the bacterial mechanosensitive ion channel of large …

A 2H solid-state NMR spectroscopic investigation of biomimetic bicelles containing cholesterol and polyunsaturated phosphatidylcholine

RE Minto, PR Adhikari, GA Lorigan - Chemistry and physics of lipids, 2004 - Elsevier
Deuterium solid-state NMR spectroscopy was used to qualitatively study the effects of both 1-
palmitoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine (PLiPC) and cholesterol on …

Single lipid bilayer deposition on polymer surfaces using bicelles

Q Saleem, Z Zhang, A Petretic, CC Gradinaru… - …, 2015 - ACS Publications
A lipid bilayer was deposited on a 3 μm diameter polystyrene (PS) bead via hydrophobic
anchoring of bicelles containing oxyamine-bearing cholesteric moieties reacting with the …