Beyond the Human Genome Project: The Age of Complete Human Genome Sequences and Pangenome References
The Human Genome Project was an enormous accomplishment, providing a foundation for
countless explorations into the genetics and genomics of the human species. Yet for many …
countless explorations into the genetics and genomics of the human species. Yet for many …
Multiscale analysis of pangenomes enables improved representation of genomic diversity for repetitive and clinically relevant genes
Advancements in sequencing technologies and assembly methods enable the regular
production of high-quality genome assemblies characterizing complex regions. However …
production of high-quality genome assemblies characterizing complex regions. However …
euka: Robust tetrapodic and arthropodic taxa detection from modern and ancient environmental DNA using pangenomic reference graphs
NA Vogel, JD Rubin, M Swartz… - Methods in Ecology …, 2023 - Wiley Online Library
Ancient environmental DNA (aeDNA) is a crucial source of information for past
environmental reconstruction. However, the computational analysis of aeDNA involves the …
environmental reconstruction. However, the computational analysis of aeDNA involves the …
Efficient and Robust Search of Microbial Genomes via Phylogenetic Compression
Comprehensive collections approaching millions of sequenced genomes have become
central information sources in the life sciences. However, the rapid growth of these …
central information sources in the life sciences. However, the rapid growth of these …
AlcoR: alignment-free simulation, mapping, and visualization of low-complexity regions in biological data
Background Low-complexity data analysis is the area that addresses the search and
quantification of regions in sequences of elements that contain low-complexity or repetitive …
quantification of regions in sequences of elements that contain low-complexity or repetitive …
Compressive Pangenomics Using Mutation-Annotated Networks
Pangenomics is an emerging field that uses a collection of genomes of a species instead of
a single reference genome to overcome reference bias and study the within-species genetic …
a single reference genome to overcome reference bias and study the within-species genetic …
euka: Robust detection of eukaryotic taxa from modern and ancient environmental DNA using pangenomic reference graphs
Ancient environmental DNA (eDNA) is a crucial source of in-formation for past
environmental reconstruction. However, the com-putational analysis of ancient eDNA …
environmental reconstruction. However, the com-putational analysis of ancient eDNA …
[PDF][PDF] A sorting tool for improving FASTA data compression tools
The exponential growth in genomic data sequenced has led to a greater need for efficient
methods to reduce data volume without loss of information. Data compression emerges as a …
methods to reduce data volume without loss of information. Data compression emerges as a …