piRNA-guided genome defense: from biogenesis to silencing
PIWI-interacting RNAs (piRNAs) and their associated PIWI clade Argonaute proteins
constitute the core of the piRNA pathway. In gonadal cells, this conserved pathway is crucial …
constitute the core of the piRNA pathway. In gonadal cells, this conserved pathway is crucial …
The emerging role of the piRNA/piwi complex in cancer
Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …
One loop to rule them all: the ping-pong cycle and piRNA-guided silencing
The PIWI-interacting RNA (piRNA) pathway is a conserved defense mechanism that protects
the genetic information of animal germ cells from the deleterious effects of molecular …
the genetic information of animal germ cells from the deleterious effects of molecular …
[HTML][HTML] The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation
DD Jia, H Jiang, YF Zhang, Y Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Piwi-interacting RNAs (piRNAs) are a class of short chain noncoding RNAs that are
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …
PIWI-interacting RNA-36712 restrains breast cancer progression and chemoresistance by interaction with SEPW1 pseudogene SEPW1P RNA
L Tan, D Mai, B Zhang, X Jiang, J Zhang, R Bai, Y Ye… - Molecular cancer, 2019 - Springer
Background Breast cancer is one of the most common malignancies and the major cause of
cancer-related death in women. Although the importance of PIWI-interacting RNAs (piRNAs) …
cancer-related death in women. Although the importance of PIWI-interacting RNAs (piRNAs) …
Piwi-interacting RNAs in cancer: emerging functions and clinical utility
PIWI-interacting RNAs (piRNAs) are emerging players in cancer genomics. Originally
described in the germline, there are over 20,000 piRNA genes in the human genome. In …
described in the germline, there are over 20,000 piRNA genes in the human genome. In …
Panoramix enforces piRNA-dependent cotranscriptional silencing
The Piwi-interacting RNA (piRNA) pathway is a small RNA–based innate immune system
that defends germ cell genomes against transposons. In Drosophila ovaries, the nuclear …
that defends germ cell genomes against transposons. In Drosophila ovaries, the nuclear …
Silencio/CG9754 connects the Piwi–piRNA complex to the cellular heterochromatin machinery
G Sienski, J Batki, KA Senti, D Dönertas… - Genes & …, 2015 - genesdev.cshlp.org
The repression of transposable elements in eukaryotes often involves their transcriptional
silencing via targeted chromatin modifications. In animal gonads, nuclear Argonaute …
silencing via targeted chromatin modifications. In animal gonads, nuclear Argonaute …
The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility
Abstract Pachytene PIWI-interacting RNAs (piRNAs), which comprise> 80% of small RNAs
in the adult mouse testis, have been proposed to bind and regulate target RNAs like …
in the adult mouse testis, have been proposed to bind and regulate target RNAs like …
Genomic signatures associated with maintenance of genome stability and venom turnover in two parasitoid wasps
Parasitoid wasps are rapidly developing as a model for evolutionary biology. Here we
present chromosomal genomes of two Anastatus wasps, A. japonicus and A. fulloi, and …
present chromosomal genomes of two Anastatus wasps, A. japonicus and A. fulloi, and …