Biosynthesis and export of bacterial lipopolysaccharides
C Whitfield, MS Trent - Annual review of biochemistry, 2014 - annualreviews.org
Lipopolysaccharide molecules represent a unique family of glycolipids based on a highly
conserved lipid moiety known as lipid A. These molecules are produced by most gram …
conserved lipid moiety known as lipid A. These molecules are produced by most gram …
Lipid A modification systems in gram-negative bacteria
CRH Raetz, CM Reynolds, MS Trent… - Annu. Rev …, 2007 - annualreviews.org
The lipid A moiety of lipopolysaccharide forms the outer monolayer of the outer membrane of
most gram-negative bacteria. Escherichia coli lipid A is synthesized on the cytoplasmic …
most gram-negative bacteria. Escherichia coli lipid A is synthesized on the cytoplasmic …
[HTML][HTML] Molecular engineering of antimicrobial peptides: Microbial targets, peptide motifs and translation opportunities
The global public health threat of antimicrobial resistance has led the scientific community to
highly engage into research on alternative strategies to the traditional small molecule …
highly engage into research on alternative strategies to the traditional small molecule …
Lipopolysaccharide: Biosynthetic pathway and structure modification
X Wang, PJ Quinn - Progress in lipid research, 2010 - Elsevier
Lipopolysaccharide that constitutes the outer leaflet of the outer membrane of most Gram-
negative bacteria is referred to as an endotoxin. It is comprised of a hydrophilic …
negative bacteria is referred to as an endotoxin. It is comprised of a hydrophilic …
Flexibility in the ABC transporter MsbA: Alternating access with a twist
A Ward, CL Reyes, J Yu, CB Roth… - Proceedings of the …, 2007 - National Acad Sciences
ATP-binding cassette (ABC) transporters are integral membrane proteins that translocate a
wide variety of substrates across cellular membranes and are conserved from bacteria to …
wide variety of substrates across cellular membranes and are conserved from bacteria to …
Bacterial strategies of resistance to antimicrobial peptides
Antimicrobial peptides (AMPs) are a key component of the host's innate immune system,
targeting invasive and colonizing bacteria. For successful survival and colonization of the …
targeting invasive and colonizing bacteria. For successful survival and colonization of the …
[HTML][HTML] Recognition of lipid A variants by the TLR4-MD-2 receptor complex
N Maeshima, RC Fernandez - Frontiers in cellular and infection …, 2013 - frontiersin.org
Lipopolysaccharide (LPS) is a component of the outer membrane of almost all Gram-
negative bacteria and consists of lipid A, core sugars, and O-antigen. LPS is recognized by …
negative bacteria and consists of lipid A, core sugars, and O-antigen. LPS is recognized by …
Invited review: diversity of endotoxin and its impact on pathogenesis
MS Trent, CM Stead, AX Tran… - Journal of endotoxin …, 2006 - journals.sagepub.com
Lipopolysaccharide or LPS is localized to the outer leaflet of the outer membrane and serves
as the major surface component of the bacterial cell envelope. This remarkable glycolipid is …
as the major surface component of the bacterial cell envelope. This remarkable glycolipid is …
Modulating the innate immune response by combinatorial engineering of endotoxin
BD Needham, SM Carroll, DK Giles… - Proceedings of the …, 2013 - National Acad Sciences
Despite its highly inflammatory nature, LPS is a molecule with remarkable therapeutic
potential. Lipid A is a glycolipid that serves as the hydrophobic anchor of LPS and …
potential. Lipid A is a glycolipid that serves as the hydrophobic anchor of LPS and …
Endotoxins: lipopolysaccharides of gram-negative bacteria
X Wang, PJ Quinn - Endotoxins: structure, function and recognition, 2010 - Springer
Endotoxin refers lipopolysaccharide that constitutes the outer leaflet of the outer membrane
of most Gram-negative bacteria. Lipopolysaccharide is comprised of a hydrophilic …
of most Gram-negative bacteria. Lipopolysaccharide is comprised of a hydrophilic …