Carbosilane dendritic nanostructures, highly versatile platforms for pharmaceutical applications

FJ de la Mata, R Gómez, J Cano… - Wiley …, 2023 - Wiley Online Library
Dendrimers are multifunctional molecules with well‐defined size and structure due to the
step‐by‐step synthetic procedures required in their preparation. Dendritic constructs based …

Advances in metal-based nano drugs and diagnostic probes for tumor

J Ding, Z He, Y Zhai, L Ye, J Ji, X Yang… - Coordination Chemistry …, 2024 - Elsevier
Tumors, particularly malignant ones, seriously impact human health. Numerous studies
have demonstrated the exceptional potential of metal-based nanosystems, both as drugs …

Dendrimer-mediated delivery of DNA and RNA vaccines

LA Kisakova, EK Apartsin, LF Nizolenko, LI Karpenko - Pharmaceutics, 2023 - mdpi.com
DNA and RNA vaccines (nucleic acid-based vaccines) are a promising platform for vaccine
development. The first mRNA vaccines (Moderna and Pfizer/BioNTech) were approved in …

In vitro validation of the therapeutic potential of dendrimer-based nanoformulations against tumor stem cells

N Knauer, V Arkhipova, G Li, M Hewera… - International Journal of …, 2022 - mdpi.com
Tumor cells with stem cell properties are considered to play major roles in promoting the
development and malignant behavior of aggressive cancers. Therapeutic strategies that …

A review of porphyrin dendrimers as light-harvesting versatile platforms

M Vonlanthen, F Cuétara-Guadarrama… - Dyes and …, 2023 - Elsevier
Porphyrins are essential constituents of biological systems and play critical roles in light
harvesting, oxygen transport, and biocatalysis. The exceptional photophysical and …

“Click” Chemistry for the Functionalization of Graphene Oxide with Phosphorus Dendrons: Synthesis, Characterization and Preliminary Biological Properties

O Alami, R Laurent, M Tassé, Y Coppel… - … A European Journal, 2023 - Wiley Online Library
Two families of phosphorhydrazone dendrons having either an azide or an alkyne linked to
the core and diverse types of pyridine derivatives as terminal functions have been …

Single-component physical hydrogels of dendritic molecules

E Apartsin, AM Caminade - Journal of Composites Science, 2023 - mdpi.com
Hydrogels are hydrophilic, three-dimensional networks able to imprison large amounts of
water and are largely used in pharmaceutical formulations. Hydrogels are frequently …

Effects of cationic dendrimers and their complexes with microRNAs on immunocompetent cells

N Knauer, E Pashkina, A Aktanova, O Boeva… - Pharmaceutics, 2022 - mdpi.com
Short regulatory oligonucleotides are considered prospective tools for immunotherapy.
However, they require an adequate carrier to deliver potential therapeutics into immune …

Triazine–carbosilane dendrimersomes enhance cellular uptake and phototoxic activity of rose bengal in basal cell skin carcinoma cells

K Sztandera, M Gorzkiewicz, M Bątal… - International journal …, 2022 - Taylor & Francis
Background The search for new formulations for photodynamic therapy is intended to
improve the outcome of skin cancer treatment using significantly reduced doses of …

Amphiphilic triazine-phosphorus metallodendrons possessing anti-cancer stem cell activity

EK Apartsin, N Knauer, UD Kahlert, AM Caminade - Pharmaceutics, 2022 - mdpi.com
Dendritic molecules bearing metal complexes in their structure (metallodendrimers and
metallodendrons) are considered prospective therapeutic entities. In particular …