Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology

MSO Pijeira, H Viltres, J Kozempel, M Sakmár… - EJNMMI …, 2022 - Springer
Background Recent advances in nanotechnology have offered new hope for cancer
detection, prevention, and treatment. Nanomedicine, a term for the application of …

Rheumatoid arthritis: Pathophysiology, current therapeutic strategies and recent advances in targeted drug delivery system

R Deshmukh - Materials Today Communications, 2023 - Elsevier
Recent advancements in technology and science thoroughly changed the basic
understanding and treatment approach of rheumatoid arthritis (RA). RA is a chronic …

Dexamethasone-loaded radially mesoporous silica nanoparticles for sustained anti-inflammatory effects in rheumatoid arthritis

SJ Kim, Y Choi, KT Min, S Hong - Pharmaceutics, 2022 - mdpi.com
Radially mesoporous silica nanoparticles (RMSNs) with protonated amine functionality are
proposed to be a dexamethasone (Dex) carrier that could achieve a sustained anti …

[223Ra] RaCl2 nanomicelles showed potent effect against osteosarcoma: targeted alpha therapy in the nanotechnology era

Y Yang, LMR Alencar, MSO Pijeira, BS Batista… - Drug Delivery, 2022 - Taylor & Francis
The treatment of bone metastatsis as primary bone cancer itself is still a challenge. The use
od radium dichloride ([223Ra] RaCl2) has emerged in the last few years as one of the best …

Fabrication and optimization of itraconazole-loaded zein-based nanoparticles in coated capsules as a promising colon-targeting approach pursuing opportunistic …

S Adel, RH Fahmy, I Elsayed, MI Mohamed… - Drug Delivery and …, 2023 - Springer
Abstract Itraconazole (ITZ), a broad-spectrum antifungal drug, was formulated into colon-
targeting system aiming to treat opportunistic colonic fungal infections that commonly infect …

Insight into Drug Loading Regulated Micellar Rigidity by Nuclear Magnetic Resonance

X Hu, Y Sun, X Zhou, B Zhang, H Guan, F Xia, S Gui… - ACS …, 2022 - ACS Publications
The rigidity of polymeric micelles plays an important role in their biological behaviors.
However, how drug loading affects the rigidity of polymeric micelles remains elusive. Herein …

Tofacitinib enhances IGF1 via inhibiting STAT6 transcriptionally activated-miR-425-5p to ameliorate inflammation in RA-FLS

Y Liu, J Peng, X Xiong, L Cheng, X Cheng - Molecular and Cellular …, 2022 - Springer
Rheumatoid arthritis (RA) is a systemic autoimmune disease, which has been reported
closely associated with the dysfunction of the Janus kinase (JAK)/signal transducer and …

Methotrexate-Loaded Surface-Modified Solid Lipid Nanoparticles Targeting Cancer Expressing COX-2 Enzyme

S Patra, J Dey, S Kar, A Chakraborty, M Tawate - Langmuir, 2024 - ACS Publications
Cancer is a major public health problem worldwide, and it is the second leading cause of
death of humans in the world. The present study has been directed toward the preparation of …

Thermally-responsive and reduced glutathione-sensitive folate-targeted nanocarrier based on alginate and pluronic F127 for on-demand release of methotrexate

NQ Vu, TT Nguyen, THT Do, TKT Pham… - International Journal of …, 2024 - Elsevier
A specific rheumatoid arthritis (RA)-microenvironment-triggered nanocarrier for RA treatment
of a first-line antirheumatic drug (Methotrexate, MTX) has been proposed. Reduced …

Spectroscopic and computational approach to study the interacting mechanism of drug-adenine complex

C Sonia, TG Devi, T Karlo - Spectroscopy Letters, 2022 - Taylor & Francis
The biomolecular complex, Adenine and Rheumatoid Arthritis drug are characterized using
vibrational spectroscopy and density functional theory. The spectral characterization of the …