The brain regulatory program predates central nervous system evolution

D Faltine-Gonzalez, J Havrilak, MJ Layden - Scientific Reports, 2023 - nature.com
Understanding how brains evolved is critical to determine the origin (s) of centralized
nervous systems. Brains are patterned along their anteroposterior axis by stripes of gene …

NvPrdm14d-expressing neural progenitor cells contribute to non-ectodermal neurogenesis in Nematostella vectensis

QIB Lemaître, N Bartsch, IU Kouzel… - Nature …, 2023 - nature.com
Neurogenesis has been studied extensively in the ectoderm, from which most animals
generate the majority of their neurons. Neurogenesis from non-ectodermal tissue is, in …

Developmental cell fate choice employs two distinct cis regulatory strategies

MJ Delás, CM Kalaitzis, T Fawzi, M Demuth, I Zhang… - bioRxiv, 2022 - biorxiv.org
In many developing tissues the patterns of gene expression that assign cell fate are
organised by secreted signals functioning in a graded manner over multiple cell diameters …