Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …

All organisms produce specialized organic molecules, ranging from small volatile chemicals
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …

Natural microbial communities are phylogenetically and metabolically diverse. In addition to
underexplored organismal groups, this diversity encompasses a rich discovery potential for …

Covering: 2016 to 2021 With genetic information available for hundreds of thousands of
organisms in publicly accessible databases, scientists have an unprecedented opportunity …

Covering: up to 2021 Metagenomics has yielded massive amounts of sequencing data
offering a glimpse into the biosynthetic potential of the uncultivated microbial majority. While …

Actinomycetes have been proven to be an excellent source of secondary metabolites for
more than half a century. Exhibiting various bioactivities, they provide valuable approved …

Broad substrate tolerance of ribosomally synthesized and post-translationally modified
peptide (RiPP) biosynthetic enzymes has allowed numerous strategies for RiPP …

Lipopeptides represent a large group of microbial natural products that include important
antibacterial and antifungal drugs and some of the most-powerful known biosurfactants. The …

Natural products remain a critical source of medicines and drug leads. One of the most
rapidly growing superclasses of natural products is RiPPs: ribosomally synthesized and …

The past decade has seen impressive advances in understanding the biosynthesis of
ribosomally synthesized and posttranslationally modified peptides (RiPPs). One of the most …