Abstract Introduction Prader-Willi syndrome (PWS) is a multisystemic complex genetic
disorder caused by lack of expression of genes on the paternally inherited chromosome …

This document summarises the conclusions of a European Respiratory Society Task Force
on the diagnosis and management of obstructive sleep disordered breathing (SDB) in …

Prader-Willi syndrome is characterized by severe infantile hypotonia with poor suck and
failure to thrive; hypogonadism causing genital hypoplasia and pubertal insufficiency; …

Context: Recombinant human GH (rhGH) therapy in Prader-Willi syndrome (PWS) has been
used by the medical community and advocated by parental support groups since its …

Objective: The objective of the study was to provide recommendations for the diagnosis and
management of Prader-Willi syndrome throughout the life span to guide clinical practice …

Prader-Willi syndrome is a complex disorder affecting multiple systems with many
manifestations relating to hypothalamic insufficiency. Major findings include infantile …

Abstract Background Prader-Willi syndrome (PWS) is a rare, complex, neurodevelopmental
genetic disorder that is associated with hyperphagia and morbid obesity in humans and …

Abstract Background: Between 1985 and 2006, the National Cooperative Growth Study
(NCGS) monitored the safety and efficacy of recombinant human growth hormone (rhGH) in …

Prader-Willi syndrome (PWS) is characterized by severe hypotonia and feeding difficulties in
early infancy, followed in later infancy or early childhood by excessive eating and gradual …

Abstract Background Prader–Willi syndrome (PWS) is a complex neuroendocrine disorder
affecting approximately 1/15,000–1/30,000 people. Unmet medical needs of individuals with …