Extracellular vesicles in coronary artery disease

CM Boulanger, X Loyer, PE Rautou… - Nature reviews …, 2017 - nature.com
Membrane vesicles released in the extracellular space are composed of a lipid bilayer
enclosing soluble cytosolic material and nuclear components. Extracellular vesicles include …

Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases

A Ståhl, K Johansson, M Mossberg, R Kahn… - Pediatric …, 2019 - Springer
Extracellular vesicles are cell-derived membrane particles ranging from 30 to 5,000 nm in
size, including exosomes, microvesicles, and apoptotic bodies. They are released under …

Physical exercise induces rapid release of small extracellular vesicles into the circulation

C Frühbeis, S Helmig, S Tug, P Simon… - Journal of …, 2015 - Taylor & Francis
Cells secrete extracellular vesicles (EVs) by default and in response to diverse stimuli for the
purpose of cell communication and tissue homeostasis. EVs are present in all body fluids …

Extracellular vesicles in cardiovascular disease: potential applications in diagnosis, prognosis, and epidemiology

F Jansen, G Nickenig, N Werner - Circulation research, 2017 - Am Heart Assoc
Extracellular vesicles originate from diverse subcellular compartments and are released in
the extracellular space. By transferring their cargoes into target cells and tissues, they now …

An estimate of extracellular vesicle secretion rates of human blood cells

M Auber, P Svenningsen - Journal of Extracellular Biology, 2022 - Wiley Online Library
Extracellular vesicles (EVs) have been implicated in the intercellular transfer of RNA and
proteins through cellular secretion into the extracellular space. In blood plasma, circulating …

Platelets in cardiac ischaemia/reperfusion injury: a promising therapeutic target

M Ziegler, X Wang, K Peter - Cardiovascular research, 2019 - academic.oup.com
Acute myocardial infarction (AMI) is the single leading cause of mortality and morbidity
worldwide. A key component of AMI therapy is the timely reopening of occluded vessels to …

The role of microvesicles and its active molecules in regulating cellular biology

YM Lv, J Tan, Y Miao, Q Zhang - Journal of Cellular and …, 2019 - Wiley Online Library
Cell‐derived microvesicles are membrane vesicles produced by the outward budding of the
plasma membrane and released by almost all types of cells. These have been considered …

The pathophysiological role of platelet-derived extracellular vesicles

M Mabrouk, F Guessous, A Naya… - … in thrombosis and …, 2023 - thieme-connect.com
Platelets are very abundant in the blood, where they play a role in hemostasis, inflammation,
and immunity. When activated, platelets undergo a conformational change that allows the …

Exosomes and cardiovascular protection

SM Davidson, K Takov, DM Yellon - Cardiovascular drugs and therapy, 2017 - Springer
Most, if not all, cells of the cardiovascular system secrete small, lipid bilayer vesicles called
exosomes. Despite technical challenges in their purification and analysis, exosomes from …

Acute kidney injury by ischemia/reperfusion and extracellular vesicles

MØ Nørgård, P Svenningsen - International Journal of Molecular Sciences, 2023 - mdpi.com
Acute kidney injury (AKI) is often caused by ischemia-reperfusion injury (IRI). IRI significantly
affects kidney metabolism, which elicits pro-inflammatory responses and kidney injury. The …