The novel, clinical-stage soluble guanylate cyclase activator BI 685509 protects from disease progression in models of renal injury and disease
GA Reinhart, PC Harrison, K Lincoln, H Chen… - … of Pharmacology and …, 2023 - ASPET
Activation of soluble guanylate cyclase (sGC) to restore cyclic guanosine monophosphate
(cGMP) and improve functionality of nitric oxide (NO) pathways impaired by oxidative stress …
(cGMP) and improve functionality of nitric oxide (NO) pathways impaired by oxidative stress …
Preclinical Pharmacokinetic Studies of a Novel Diuretic Inhibiting Urea Transporters
Urea transporter (UT) inhibitors are a class of promising novel diuretics that do not cause the
imbalance of Na+, K+, Cl−, and other electrolytes. In our previous studies, 25a, a promising …
imbalance of Na+, K+, Cl−, and other electrolytes. In our previous studies, 25a, a promising …