Current evidence links oxidative stress (OS) to male infertility, reduced sperm motility, sperm
DNA damage and increased risk of recurrent abortions and genetic diseases. A review of …

Varicocele has been associated with reduced male reproductive potential. With the
advances in biomolecular techniques, it has been possible to better understand the …

Sperm DNA fragmentation (sDF) represents a threat to male fertility, human reproduction
and the health of the offspring. The causes of sDF are still unclear, even if apoptosis …

Objective: To examine the relationship between sperm chromatin defects, evaluated by the
flow cytometric (FCM) sperm chromatin structure assay (SCSA), and the probability of a …

The literature contains conflicting evidence regarding the existence of DNA damage in
spermatozoa from infertile male patients. To examine this phenomenon, we have studied …

DNA damage in the male germ line has been associated with poor semen quality, low
fertilization rates, impaired preimplantation development, increased abortion and an …

BACKGROUND: The aim of this study was to examine the role of apoptosis and reactive
oxygen species (ROS) in inducing DNA damage in ejaculated spermatozoa. METHODS: We …

The molecular basis of many forms of male infertility is poorly defined. One area of research
that has been studied intensely is the integrity of the DNA in the nucleus of mature …

DNA damage is a common feature of human spermatozoa with purported links to poor rates
of conception, impaired embryonic development, an increased incidence of miscarriage and …

Numerous studies have shown the presence of DNA strand breaks in human ejaculated
spermatozoa. The nature of this nuclear anomaly and its relationship to patient etiology is …