cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”
The World Health Organization (WHO) central nervous system tumor classification
represents the primary source of updates on diagnostic classes, grades and criteria [17] …
represents the primary source of updates on diagnostic classes, grades and criteria [17] …
Leptomeningeal spread in glioblastoma: diagnostic and therapeutic challenges
Background Glioblastoma (GBM) is the most common and aggressive primary malignant
brain tumor. Leptomeningeal spread (LMS) is a severe complication of GBM, raising …
brain tumor. Leptomeningeal spread (LMS) is a severe complication of GBM, raising …
[HTML][HTML] Diffuse midline gliomas with histone H3 K27M mutation in adults and children: a retrospective series of 164 cases
L Zheng, J Gong, T Yu, Y Zou, M Zhang… - The American Journal …, 2022 - journals.lww.com
Diffuse midline glioma, H3 K27M-mutant (H3 K27M-mt DMG), is a rare and highly
aggressive tumor that is more common in children than in adults. Few studies have …
aggressive tumor that is more common in children than in adults. Few studies have …
Prognostic value of test (s) for O6‐methylguanine–DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma …
A McAleenan, C Kelly, F Spiga… - Cochrane Database …, 2021 - cochranelibrary.com
Background Glioblastoma is an aggressive form of brain cancer. Approximately five in 100
people with glioblastoma survive for five years past diagnosis. Glioblastomas that have a …
people with glioblastoma survive for five years past diagnosis. Glioblastomas that have a …
[HTML][HTML] The interaction between TERT promoter mutation and MGMT promoter methylation on overall survival of glioma patients: a meta-analysis
Background There are controversial results concerning the prognostic implication of TERT
promoter mutation in glioma patients concerning MGMT status. In this meta-analysis, we …
promoter mutation in glioma patients concerning MGMT status. In this meta-analysis, we …
Imaging characteristics of adult H3 K27M-mutant gliomas
T Qiu, A Chanchotisatien, Z Qin, J Wu, Z Du… - Journal of …, 2019 - thejns.org
OBJECTIVE H3 K27M-mutant gliomas present heterogeneously in terms of pathology,
imaging, and prognosis. This study aimed to summarize the imaging characteristics of adult …
imaging, and prognosis. This study aimed to summarize the imaging characteristics of adult …
[HTML][HTML] TERT promoter wild-type glioblastomas show distinct clinical features and frequent PI3K pathway mutations
EA Williams, JJ Miller, SS Tummala, T Penson… - Acta neuropathologica …, 2018 - Springer
TERT promoter (TERT p) mutations are found in the majority of World Health Organization
(WHO) grade IV adult IDH wild-type glioblastoma (IDH-wt GBM). Here, we characterized the …
(WHO) grade IV adult IDH wild-type glioblastoma (IDH-wt GBM). Here, we characterized the …
Molecular characterization of adult tumors diagnosed as cerebellar glioblastomas identifies subgroups associated with prognosis
T Picart, D Poncet, M Barritault, L Bauchet… - The American Journal …, 2023 - journals.lww.com
Adult tumors diagnosed as cerebellar glioblastoma (cGBM) are rare and their optimal
classification remains to be determined. The aim of this study was to identify subgroups of …
classification remains to be determined. The aim of this study was to identify subgroups of …
Cerebellar glioblastoma: a clinical series with contemporary molecular analysis
B Hong, R Banan, A Christians, M Nakamura… - Acta …, 2018 - Springer
Background Glioblastomas (GBM) are localized in only less than 1% of patients in the
cerebellum. Therefore, tumor characteristics, survival, and the efficacy of therapies are not …
cerebellum. Therefore, tumor characteristics, survival, and the efficacy of therapies are not …
[HTML][HTML] Cerebellar high-grade glioma: a translationally oriented review of the literature
Simple Summary High-grade glial cancers typically arise in the cerebral hemispheres and
only rarely elsewhere in the brain. Historically, such tumors arising in the cerebellum have …
only rarely elsewhere in the brain. Historically, such tumors arising in the cerebellum have …