Placental tissues encompass all the tissues which support fetal development, including the
placenta, placental membrane, umbilical cord, and amniotic fluid. Since the 1990s there has …

Various types of cellular injection have become a popular and costly treatment option for
patients with knee osteoarthritis despite a paucity of literature establishing relative efficacy to …

Orthobiologic agents, including platelet-rich plasma, connective tissue progenitor cells
derived from bone marrow, adipose, and other tissues, and purified cytokines and small …

This 2020 NBA Orthobiologics Consensus Statement provides a concise summary of
available literature and practical clinical guidelines for team physicians and players. We …

Background: There has been a recent surge in health-care providers offering stem cell
therapy (SCT) to patients with musculoskeletal disease. The purpose of this study was to …

BACKGROUND AND PURPOSE In the United States, the number of clinics offering “stem-
cell therapy” is estimated to be well over 1000. 1, 2 Many clinics advertise unproven and …

Background: Umbilical cord (UC) connective tissues contain plastic-adherent, colony
forming unit–fibroblasts (CFU-Fs) amenable to culture expansion for potential therapeutic …

Aim: This study compared growth kinetics of human amniotic fluid stem cells (hAFSCs) in
different maternal age groups and two different media of AmnioMAX and Dulbecco's …

Objective Amnion products are used in various musculoskeletal surgeries and as injections
for joint pain with conflicting reports of cell viability and protein contents. The objective of this …

Orthobiologics are rapidly growing in use given their potential to augment healing for
multiple musculoskeletal conditions. Orthobiologics consist of a variety of treatments …