Mantle cell lymphoma is a B cell malignancy in which constitutive dysregulation of cyclin D1
and the cell cycle, disruption of DNA damage response pathways, and activation of cell …

The transcription factor SOX11 (SRY-related high-mobility-group (HMG) box 11), a member
of the SOXC group, is expressed during embryogenesis but largely absent in most adult …

Mantle cell lymphoma (MCL) is one of the most aggressive lymphoid neoplasms whose
pathogenesis is not fully understood. The neural transcription factor SOX11 is …

To investigate the three-dimensional (3D) genome architecture across normal B cell
differentiation and in neoplastic cells from different subtypes of chronic lymphocytic leukemia …

We analyzed the in silico purified DNA methylation signatures of 82 mantle cell lymphomas
(MCL) in comparison with cell subpopulations spanning the entire B cell lineage. We …

BACKGROUND & AIMS: Crohn's disease is an inflammatory bowel disease induced by
multiple genetic and environmental factors. Genome-wide association studies have …

SOX11 is overexpressed in several solid tumors and in the vast majority of aggressive
mantle cell lymphomas (MCLs). We have recently proven that SOX11 silencing reduces …

Aggressive double-and triple-hit (DH/TH) diffuse large B-cell lymphomas (DLBCLs) feature
activation of Hsp90 stress pathways. Herein, we show that Hsp90 controls …

Sex-determining region Y-related high-mobility-group box transcription factor 11 (SOX11) is
an essential member of the SOX transcription factors and has been highlighted as an …

SOX11 is a relevant element in the pathogenesis of MCL and has been instrumental to
identify two distinct clinicobiological subtypes of this tumor. Further studies should clarify the …