Mendelian variants can determine both insemination success and neonatal survival and
thus influence fertility and rearing success of cattle. We present 24 deficient homozygous …

Genetic disorders arise from alterations in the hereditary information encoded in DNA,
leading to potential detrimental effects on the well-being and vitality of organisms. Within the …

The influence of various risk factors such as aging, intricate cellular molecular processes,
and lifestyle factors like smoking, alcohol consumption, caffeine intake, and occupational …

Background Homozygous recessive deleterious mutations can cause embryo/fetal or
neonatal lethality, or genetic defects that affect female fertility and animal welfare. In …

Background This study was carried out on the two Braunvieh populations reared in
Switzerland, the dairy Brown Swiss (BS) and the dual-purpose Original Braunvieh (OB). We …

Simple Summary Today's Swiss Simmental represents a local dual-purpose breed of cattle.
Within closed populations, deleterious variants can reach problematic frequencies …

We recently demonstrated that the Lacaune deficient homozygous haplotype 6 (LDHH6)
potentially hosts a recessive perinatal lethal mutation in Lacaune dairy sheep mapped on …

Background. Hepatocellular carcinoma (HCC) is one of the most common malignancies
globally, but its molecular mechanism is unclear. Abnormal expression of centromere …

Widespread genotyping has enabled the identification of putative recessive mutations that
affect fertility through early embryonic fetal loss, or compromise neonate or calf viability. The …

The deterioration in reproductive performance in association with low fertility leads to
significant economic losses on dairy farms. The uterine microbiota has begun to attract …