Acute kidney injury occurs with kidney transplantation and too frequently progresses to the
clinical diagnosis of delayed graft function (DGF). Poor kidney function in the first week of …

Effective immunosuppression is an essential pre-requisite for successful organ
transplantation and improvements in outcome after transplantation have to a large extent …

Background There are few comparisons of antibody induction therapy allowing early
glucocorticoid withdrawal in renal-transplant recipients. The purpose of the present study …

Since the introduction of organ transplantation into medical practice, progress and optimism
have been abundant. Improvements in immunosuppressive drugs and ancillary care have …

Remarkable progress has been made in islet transplantation over a span of 40 years. Once
just an experimental curiosity in mice, this therapy has moved forward, and can now provide …

Antilymphocyte therapies are widely used for immunosuppression in solid organ
transplantation. These agents have varied mechanisms of action, with resulting differences …

Background. Alemtuzumab is being increasingly used for the prevention and/or treatment of
acute allograft rejection in organ transplant recipients. We assessed the risks of infection in …

Abstract Introduction CD52 (Campath-1 antigen), a glycoprotein of 12 amino acids anchored
to glycosylphosphatidylinositol, is widely expressed on the cell surface of immune cells …

Transplant patients are at the risk for posttransplant lymphoproliferative disease (PTLD), a
virally‐driven malignancy. Induction with the depleting antibody preparations Thymoglobulin …

The achievement of an immunosuppression (IS)-free state after transplantation represents
the ultimate goal of any immunosuppressive regimen. While clinical operational tolerance …