Osteoporosis has been defined as the silent disease of the 21st century, becoming a public
health risk due to its severity, chronicity and progression and affecting mainly …

Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …

Skeletal-related disorders such as arthritis, bone cancer, osteosarcoma, and osteoarthritis
are among the most common reasons for mortality in humans at present. Nanostructured …

Bone tissue is continuously remodeled through the concerted actions of bone cells, which
include bone resorption by osteoclasts and bone formation by osteoblasts, whereas …

Bones as an alive organ consist of about 70% mineral and 30% organic component. About
200 million people are suffering from osteopenia and osteoporosis around the world. There …

Periodontal disease represents a group of oral inflammatory infections initiated by oral
pathogens which exist as a complex biofilms on the tooth surface and cause destruction to …

Abstract The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital
component of the G protein-coupled receptor (GPCR) family and is found primarily on the …

Osteoimmunology is a new subject which focuses on the communication between the
immune and the skeletal systems. Both the immune system and bone communicate with …

In 1892, JL Wolff proposed that bone could respond to mechanical and biophysical stimuli
as a dynamic organ. This theory presents a unique opportunity for investigations on bone …

Calcium is an essential element that plays numerous biological functions in the human
body, of which one of the most important is skeleton mineralization. Bone is a mineralized …