Nowadays, orthodontic treatment has become increasingly popular. However, the biological
mechanisms of orthodontic tooth movement (OTM) have not been fully elucidated. We were …

Periodontal tissue regeneration is the ultimate goal of the treatment for periodontitis-affected
teeth. The success of regenerative modalities relies heavily on the utilization of appropriate …

In recent years, tissue engineering studies have proposed several approaches to
regenerate periodontium based on the use of three-dimensional (3D) tissue scaffolds alone …

Objectives The aim of the present systematic review was to offer a timeline of the events
taking place during orthodontic tooth movement (OTM). Materials and methods Electronic …

Objectives Many in vitro studies have investigated the mechanism by which mechanical
signals are transduced into biological signals that regulate bone homeostasis via …

The bone remodeling process in response to orthodontic forces requires the activity of
osteoclasts to allow teeth to move in the direction of the force applied. Receptor activator of …

Objective: To evaluate the function of Piezo1, an evolutionarily conserved mechanically
activated channel, in periodontal ligament (PDL) tissue homeostasis under compressive …

When an orthodontic force is applied, the periodontal tissues express extensive
macroscopic and microscopic changes, leading to alterations in 5 microenvironments …

Fibroblasts are cells of mesenchymal origin. They are responsible for the production of most
extracellular matrix in connective tissues and are essential for wound healing and repair. In …

Objectives The aim of this study was to investigate and compare the changes in human
periodontal ligament fibroblasts (HPdLFs) and osteoblasts (HOBs) after the application of …