Neuroblastoma is an embryonal malignancy that affects normal development of the adrenal
medulla and paravertebral sympathetic ganglia in early childhood. Extensive studies have …

Smooth muscle cell (SMC) differentiation is an important process during vascular
development. The highly differentiated mature SMCs play critical roles in maintaining …

MicroRNAs (miRNAs) are regulators of myriad cellular events, but evidence for a single
miRNA that can efficiently differentiate multipotent stem cells into a specific lineage or …

Activating anaplastic lymphoma kinase (ALK) mutations were recently detected in most
familial and 10% of sporadic neuroblastomas. However, the role of mutated ALK in …

Cranial neural crest cells give rise to ectomesenchymal derivatives such as cranial bones,
cartilage, smooth muscle, dentin, as well as melanocytes, corneal endothelial cells, and …

Neuroblastoma is an embryonal tumor with a heterogeneous clinical course. The tumor is
presumed to be derived from the neural crest, but the cells of origin remain to be determined …

Development of in vitro models by which to study smooth muscle cell (SMC) differentiation
has been hindered by some peculiarities intrinsic to these cells, namely their different …

Schwann cells, the myelinating glia of the peripheral nervous system (PNS), originate from
multipotent neural crest cells that also give rise to other cells, including neurons …

Low-intensity pulsed ultrasound (LIPUS) acting on induced pluripotent stem cells–derived
neural crest stem cells (iPSCs–NCSCs) is considered a promising therapy to improve the …

In the adult organism, cell migration is required for physiological processes such as
angiogenesis and immune surveillance, as well as pathological events such as tumor …