[HTML][HTML] The emerging role of the piRNA/piwi complex in cancer

Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …

Small non-coding RNA and cancer

G Romano, D Veneziano, M Acunzo… - …, 2017 - academic.oup.com
The ENCODE project has reported that at least 80% of the human genome is biologically
active, yet only a small part of human DNA encodes for protein. The massive amount of RNA …

[HTML][HTML] 2L-piRNA: a two-layer ensemble classifier for identifying piwi-interacting RNAs and their function

B Liu, F Yang, KC Chou - Molecular Therapy-Nucleic Acids, 2017 - cell.com
Involved with important cellular or gene functions and implicated with many kinds of cancers,
piRNAs, or piwi-interacting RNAs, are of small non-coding RNA with around 19–33 nt in …

[HTML][HTML] Non-coding RNAs in breast cancer: intracellular and intercellular communication

CM Klinge - Non-coding RNA, 2018 - mdpi.com
Non-coding RNAs (ncRNAs) are regulators of intracellular and intercellular signaling in
breast cancer. ncRNAs modulate intracellular signaling to control diverse cellular processes …

[HTML][HTML] Piwi-interacting RNAs in cancer: emerging functions and clinical utility

KW Ng, C Anderson, EA Marshall, BC Minatel… - Molecular cancer, 2016 - Springer
PIWI-interacting RNAs (piRNAs) are emerging players in cancer genomics. Originally
described in the germline, there are over 20,000 piRNA genes in the human genome. In …

[HTML][HTML] The biogenesis and functions of piRNAs in human diseases

X Wu, Y Pan, Y Fang, J Zhang, M Xie, F Yang… - … Therapy-Nucleic Acids, 2020 - cell.com
Piwi-interacting RNAs (piRNAs) are a novel type of small noncoding RNAs, which are 26–30
nt in length and bind to Piwi proteins. These short RNAs were originally discovered in …

piRNAs: biogenesis and their potential roles in cancer

B Guo, D Li, L Du, X Zhu - Cancer and Metastasis Reviews, 2020 - Springer
With the length of about 26–31 nt, PIWI-interacting RNA (piRNA) is a small non-coding RNA
(ncRNA) that interacts with PIWI proteins to form the piRNA silencing complex (piRISC). PIWI …

[PDF][PDF] PIWI proteins and PIWI-interacting RNA: emerging roles in cancer

YN Han, Y Li, SQ Xia, YY Zhang, JH Zheng… - Cellular Physiology and …, 2018 - karger.com
P-Element induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a type of noncoding
RNAs (ncRNAs) and interact with PIWI proteins. piRNAs were primarily described in the …

[HTML][HTML] Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

VD Martinez, EA Vucic, KL Thu, R Hubaux… - Scientific reports, 2015 - nature.com
Abstract Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline
cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues …

[HTML][HTML] Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer

MA Diamantopoulos, P Tsiakanikas… - Annals of translational …, 2018 - ncbi.nlm.nih.gov
Non-coding RNAs (ncRNAs) constitute a heterogeneous group of RNA molecules in terms
of biogenesis, biological function as well as length and structure. These biological …