Unhealthy gut, unhealthy brain: The role of the intestinal microbiota in neurodegenerative diseases

LJ Spielman, DL Gibson, A Klegeris - Neurochemistry international, 2018 - Elsevier
The number of bacterial cells living within the human body is approximately equal to, or
greater than, the total number of human cells. This dynamic population of microorganisms …

Roles and mechanisms of gut microbiota in patients with Alzheimer's disease

S Wu, X Liu, R Jiang, X Yan, Z Ling - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is the most common age-related progressive neurodegenerative
disease, characterized by a decline in cognitive function and neuronal loss, and is caused …

Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota

B Li, Y He, J Ma, P Huang, J Du, L Cao, Y Wang… - Alzheimer's & …, 2019 - Elsevier
Objective Gut microbiota changes before the onset of Alzheimer's disease (AD) and the
alterations could be detected in the stage of mild cognitive impairment (MCI). The findings …

Sex matters: impact on pathogenesis, presentation and treatment of inflammatory bowel disease

WA Goodman, IP Erkkila, TT Pizarro - Nature reviews Gastroenterology …, 2020 - nature.com
Inflammatory bowel disease (IBD), as do most chronic inflammatory disorders, displays
unique features and confers different risk factors in male and female patients. Importantly …

Association of intestinal disorders with Parkinson's disease and Alzheimer's disease: a systematic review and meta-analysis

P Fu, M Gao, KKL Yung - ACS chemical neuroscience, 2019 - ACS Publications
Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common
neurodegenerative disorders, with an overall global incidence of 40 million. Many studies …

A meta-analysis investigating the relationship between inflammation in autoimmune disease, elevated CRP, and the risk of dementia

J Cooper, Y Pastorello, M Slevin - Frontiers in Immunology, 2023 - frontiersin.org
Alzheimer's Disease (AD) represents the most common type of dementia and is becoming a
steadily increasing challenge for health systems globally. Inflammation is developing as the …

Risk of neurodegenerative diseases in patients with inflammatory bowel disease: a nationwide population-based cohort study

GH Kim, YC Lee, TJ Kim, ER Kim… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Although recent studies have reported that inflammatory
bowel disease [IBD] is associated with the development of neurodegenerative diseases via …

Inflammatory bowel disease and cardiovascular disease incidence and mortality: a meta-analysis

HH Sun, F Tian - European journal of preventive cardiology, 2018 - journals.sagepub.com
Background The risk of cardiovascular disease occurrence and death in inflammatory bowel
disease patients is still unclear. Design Meta-analysis. Methods Pertinent studies were …

Gut microbiota and Alzheimer's disease: how to study and apply their relationship

NM Nguyen, J Cho, C Lee - International journal of molecular sciences, 2023 - mdpi.com
Gut microbiota (GM), the microorganisms in the gastrointestinal tract, contribute to the
regulation of brain homeostasis through bidirectional communication between the gut and …

[HTML][HTML] Natural history of inflammatory bowel disease: a comparison between the East and the West

EM Song, SK Yang - Intestinal research, 2022 - synapse.koreamed.org
Over the past decades, there has been a rapid increase in the incidence and prevalence of
inflammatory bowel disease (IBD) in Asia. The natural history of IBD in Asian patients could …