Late-stage functionalization (LSF) introduces functional group or structural modification at
the final stage of the synthesis of natural products, drugs, and complex compounds. It is …

The amide bond represents the most fundamental functional group in numerous areas of
chemistry, such as organic synthesis, drug discovery, polymers, and biochemistry. Although …

Transition-metal-catalyzed decarbonylation via carbon–carbon bond cleavage is an
essential synthetic methodology. Given the ubiquity of carbonyl compounds, the selective …

In recent years, significant conceptual advances have taken place in the field of amide bond
cross-coupling. Mild and selective functionalization of amides by transition-metal catalysis …

Conspectus The utilization of carboxylic acid esters as electrophiles in metal-catalyzed cross-
coupling reactions is increasingly popular, as environmentally friendly and readily available …

Cross-coupling reactions are among the most powerful C–C and C–X bond forming tools in
organic chemistry. Traditionally, cross-coupling methods rely on the use of aryl halides or …

A ligand-controlled and site-selective nickel catalyzed Suzuki–Miyaura cross-coupling
reaction with aromatic esters and alkyl organoboron reagents as coupling partners was …

The amide functional group is commonly found in peptides, proteins, pharmaceutical
compounds, natural products, and polymers. The synthesis of amides is typically performed …

Considering the ubiquity of organophosphorus compounds in organic synthesis,
pharmaceutical discovery agrochemical crop protection and materials chemistry, new …

We describe a new functional group metathesis between aryl nitriles and aryl thioethers. The
catalytic system nickel/dcype is essential to achieve this fully reversible transformation in …