Heart diseases are the primary cause of mortality and morbidity worldwide which inflict a
heavy social and economic burden. Among heart diseases, most deaths are due to …

The emergence of human induced pluripotent stem cells (hiPSCs) has revealed the
potential for curing end-stage heart failure. Indeed, transplantation of hiPSC-derived …

Objectives: In 2001, Turkey performed its the first successful heart transplant. Since 2011,
765 heart transplants have been conducted among 15 heart transplant centers. The …

The recent pig heart transplant in a patient at the University of Maryland Medical Center has
stimulated renewed interest in the xenotransplantation of organs from genetically …

Expert microscopic analysis of cells obtained from frequent heart biopsies is vital for early
detection of pediatric heart transplant rejection to prevent heart failure. Detection of this rare …

Abstract Ischemia/reperfusion (I/R) injury is an inevitable process during heart transplant
and suppressing I/R injury could greatly improve the survival rate of recipients …

Background. The INTERHEART study (ClinicalTrials. gov# NCT02670408) used genome-
wide microarrays to detect rejection in endomyocardial biopsies; however, many heart …

Cardiac tissue engineering is a promising strategy to generate human cardiac tissues for
modeling cardiac diseases, screening for therapeutic drugs, and repairing the injured heart …

Importance Transplantation has transformed into a burgeoning field that is rapidly evolving
to optimize organ distribution and survival outcomes. The years since 2012 (the last …

In order to regenerate myocardial tissues with functional characteristics, we need to copy
some properties of the myocardium, such as its extracellular matrix and electrical …