[HTML][HTML] An integrated cell atlas of the lung in health and disease
Single-cell technologies have transformed our understanding of human tissues. Yet, studies
typically capture only a limited number of donors and disagree on cell type definitions …
typically capture only a limited number of donors and disagree on cell type definitions …
The role of noncoding RNA in airway allergic diseases through regulation of T cell subsets
S Cheng, Q Tang, S Xie, S Wen, H Zhang… - Mediators of …, 2022 - Wiley Online Library
Allergic rhinitis and asthma are common airway allergic diseases, the incidence of which
has increased annually in recent years. The human body is frequently exposed to allergens …
has increased annually in recent years. The human body is frequently exposed to allergens …
[HTML][HTML] EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway
C Liu, J Lu, T Yuan, L Xie, L Zhang - Scientific Reports, 2023 - nature.com
We aimed to investigate whether exosomes (Exo) affected chronic obstructive pulmonary
disease (COPD) by influencing ferroptosis of bronchial epithelial cells (BECs) and the …
disease (COPD) by influencing ferroptosis of bronchial epithelial cells (BECs) and the …
Dectin-1 acts as a non-classical receptor of Ang II to induce cardiac remodeling
S Ye, H Huang, X Han, W Luo, L Wu, Y Ye… - Circulation …, 2023 - Am Heart Assoc
Background: Cardiac remodeling in heart failure involves macrophage-mediated immune
responses. Recent studies have shown that a PRR (pattern recognition receptor) called …
responses. Recent studies have shown that a PRR (pattern recognition receptor) called …
[HTML][HTML] Unraveling the pathogenesis of asthma and chronic obstructive pulmonary disease overlap: focusing on epigenetic mechanisms
YC Chen, YP Chang, KT Huang, PY Hsu, CC Hsiao… - Cells, 2022 - mdpi.com
Asthma and COPD overlap (ACO) is characterized by patients presenting with persistent
airflow limitation and features of both asthma and COPD. It is associated with a higher …
airflow limitation and features of both asthma and COPD. It is associated with a higher …
Nasal airway microRNA profiling of infants with severe bronchiolitis and risk of childhood asthma: a multicentre prospective study
Background Severe bronchiolitis (ie bronchiolitis requiring hospitalisation) during infancy is
a major risk factor for childhood asthma. However, the exact mechanism linking these …
a major risk factor for childhood asthma. However, the exact mechanism linking these …
[HTML][HTML] MiRNA and exosomal miRNA as new biomarkers useful to phenotyping severe asthma
P Soccio, G Moriondo, D Lacedonia, P Tondo… - Biomolecules, 2023 - mdpi.com
Severe asthma (SA) is a chronic inflammatory disease of the airways. Due to the extreme
heterogeneity of symptoms, new biomarkers are currently needed. MiRNAs are non-coding …
heterogeneity of symptoms, new biomarkers are currently needed. MiRNAs are non-coding …
Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression
W Langwiński, D Szczepankiewicz, B Narożna… - Molecular …, 2022 - Elsevier
Introduction Atopic asthma and allergic rhinitis are common chronic inflammatory diseases
affecting lower airways and nasal mucosa, respectively. Several reports demonstrated …
affecting lower airways and nasal mucosa, respectively. Several reports demonstrated …
[HTML][HTML] MicroRNAs: potential biomarkers of disease severity in chronic rhinosinusitis with nasal polyps
Background and Objectives: Chronic rhinosinusitis with nasal polyps (CRwNP) has multiple
clinical presentations, and predictors of successful treatment are correlated to different …
clinical presentations, and predictors of successful treatment are correlated to different …
[HTML][HTML] Study of the regulatory mechanism of miR-26a-5p in allergic asthma
J Zhong, M Liu, S Chen, S Liu, F Li, C Li - Cells, 2022 - mdpi.com
Objective: Allergic asthma is a growing burden on national public health services due to its
high prevalence. The aim of this experiment was to investigate whether miR-26a-5p affects …
high prevalence. The aim of this experiment was to investigate whether miR-26a-5p affects …