The definition of metabolic syndrome (MetS) has undergone several changes over the years
due to the difficulty in establishing universal criteria for it. Underlying the disorders related to …

Type 2 diabetes is one of the major chronic diseases accounting for a substantial proportion
of disease burden in Western countries. The majority of the burden of type 2 diabetes is …

Excessive energy intake and reduced energy expenditure drive the development of insulin
resistance and metabolic diseases such as obesity and type 2 diabetes mellitus. Metabolic …

The aim of this work was to conduct a systematic review of human studies on metabolite/lipid
biomarkers of metabolic syndrome (MetS) and its components, and provide …

Conclusions Omics are high throughput procedures able to provide important information at
different levels (gene, mRNA, protein, metabolite level, etc.) in complicated biological …

Metabolic syndrome (MetS) is as a cluster of cardio-metabolic factors that greatly increase
the risk of chronic diseases such as type II diabetes mellitus and atherosclerotic …

Background Glycolysis/gluconeogenesis and tricarboxylic acid (TCA) cycle metabolites
have been associated with type 2 diabetes (T2D). However, the associations of these …

Dysregulation of skeletal muscle metabolism influences whole-body insulin sensitivity and
glucose homeostasis. We hypothesized that type 2 diabetes–associated alterations in the …

Background and aims Glutamate, glutamine are involved in energy metabolism, and have
been related to cardiometabolic disorders. However, their roles in the development of type-2 …

The metabolic syndrome is a multifactorial disease developed due to accumulation and
chronification of several risk factors associated with disrupted metabolism. The early …