[PDF][PDF] The role of senescence in the development of nonalcoholic fatty liver disease and progression to nonalcoholic steatohepatitis

AM Papatheodoridi, L Chrysavgis, M Koutsilieris… - …, 2020 - Wiley Online Library
In recent years, cellular senescence has generated a lot of interest among researchers
because of its involvement in both the normal aging process and common human diseases …

Epigenetics and metabolism

ST Keating, A El-Osta - Circulation research, 2015 - Am Heart Assoc
The molecular signatures of epigenetic regulation and chromatin architectures are
fundamental to genetically determined biological processes. Covalent and post-translational …

Quercetin reverses cardiac systolic dysfunction in mice fed with a high‐fat diet: role of angiogenesis

S Yu, SR Kim, K Jiang, M Ogrodnik… - Oxidative medicine …, 2021 - Wiley Online Library
Global consumption of high‐fat diets (HFD) is associated with an increased incidence of
cardiometabolic syndrome and cardiac injury, warranting identification of cardioprotective …

Exercise prevents diet-induced cellular senescence in adipose tissue

MJ Schafer, TA White, G Evans, JM Tonne… - Diabetes, 2016 - Am Diabetes Assoc
Considerable evidence implicates cellular senescence in the biology of aging and chronic
disease. Diet and exercise are determinants of healthy aging; however, the extent to which …

Increased renal cellular senescence in murine high-fat diet: effect of the senolytic drug quercetin

SR Kim, K Jiang, M Ogrodnik, X Chen, XY Zhu… - Translational …, 2019 - Elsevier
Obesity and dyslipidemia can be associated with cellular senescence, and may impair
kidney function. However, whether senescence contributes to renal dysfunction in these …

The role of adipose tissue senescence in obesity-and ageing-related metabolic disorders

Z Liu, KKL Wu, X Jiang, A Xu, KKY Cheng - Clinical science, 2020 - portlandpress.com
Adipose tissue as the largest energy reservoir and endocrine organ is essential for
maintenance of systemic glucose, lipid and energy homeostasis, but these metabolic …

The role of nutrition on epigenetic modifications and their implications on health

JC Jiménez-Chillarón, R Díaz, D Martínez, T Pentinat… - Biochimie, 2012 - Elsevier
Nutrition plays a key role in many aspects of health and dietary imbalances are major
determinants of chronic diseases including cardiovascular disease, obesity, diabetes and …

COX-2/sEH dual inhibitor alleviates hepatocyte senescence in NAFLD mice by restoring autophagy through Sirt1/PI3K/AKT/mTOR

CY Zhang, XH Tan, HH Yang, L Jin, JR Hong… - International Journal of …, 2022 - mdpi.com
We previously found that the disorder of soluble epoxide hydrolase (sEH)/cyclooxygenase-2
(COX-2)-mediated arachidonic acid (ARA) metabolism contributes to the pathogenesis of …

[HTML][HTML] The effect of eight weeks resistance and endurance training on some angiogenesis factors of hippocampus tissue in male wistar rats

M Sadegh Ghomi, M Kashef… - Journal of Sport and …, 2021 - joeppa.sbu.ac.ir
Purpose: One of the cause of adaptations due to exercise training is increased capillary
density or angiogenesis. increased blood flow to hippocampus tissue causes improvement …

مقایسة اثر تمرین تناوبی شدید و مقاومتی فزاینده بر بیان ژن ATF3 عضلة قلبی موش‌های صحرایی دیابتی نر

سفال منش, شهاب الدین, خالدی, ندا, رجبی… - نشریه فیزیولوژی ورزش و …, 2021‎ - joeppa.sbu.ac.ir
هدف: از سازوکارهای مؤثر در انجام بهتر عملکرد عضلانی در ورزشکاران، القای ظرفیت
پیش‌فعال‌سازی (PAP) در روش گرم کردن است. ازاین‌رو، پژوهش حاضر به‌منظور بررسی تأثیر گرم …