1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Vitamin D is a critical regulator of calcium and bone homeostasis. While vitamin D has
multiple effects on bone and calcium metabolism, the regulation of intestinal calcium (Ca) …

The Ca2+ extrusion function of the four mammalian isoforms of the plasma membrane
calcium ATPases (PMCAs) is well established. There is also ever-increasing detail known of …

Calcium-selective channel TRPV6 (Transient Receptor Potential channel family, Vanilloid
subfamily member 6) belongs to the TRP family of cation channels and plays critical roles in …

The intestine is the only gate for the entry of Ca to the body in humans and mammals. The
entrance of Ca occurs via paracellular and intracellular pathways. All steps of the latter …

Policy Points Child lead poisoning is associated with socioeconomic inequity and
perpetuates health inequality. Methods for testing and detection of child lead poisoning are …

Calcium is required for the functioning of numerous biological processes and is essential for
skeletal health. The major source of new calcium is from the diet. The central role of vitamin …

Data on mineral digestibility is key to understand mineral homeostasis and refine the
recommendations for the dietary intake of these nutrients. In farm animals and pets, there is …

ABSTRACT 1, 25 Dihydroxyvitamin D3 (1, 25 (OH) 2D) increases intestinal Ca absorption
when dietary Ca intake is low by inducing gene expression through the vitamin D receptor …

Although the intestine plays the major role in 1, 25-dihydroxyvitamin D3 [1, 25 (OH) 2D3]
action on calcium homeostasis, the mechanisms involved remain incompletely understood …