The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Regulated cell death is a major mechanism to eliminate damaged, infected, or superfluous
cells. Previously, apoptosis was thought to be the only regulated cell death mechanism; …

Aging is a major risk factor of high incidence and increased mortality of acute respiratory
distress syndrome (ARDS). Here, we demonstrated that persistent lung injury and high …

Acute lung injury in humans is characterized histopathologically by neutrophilic alveolitis,
injury of the alveolar epithelium and endothelium, hyaline membrane formation, and …

Reactive oxygen or nitrogen species (ROS/RNS) generated endogenously or in response to
environmental stress have long been implicated in tissue injury in the context of a variety of …

Severe sepsis, defined as sepsis with acute organ dysfunction, is associated with high
morbidity and mortality rates. The development of novel therapies for sepsis is critically …

Acute respiratory distress syndrome (ARDS) is an acute respiratory illness characterised by
bilateral chest radiographical opacities with severe hypoxaemia due to non-cardiogenic …

Background Sepsis remains a common and serious condition with significant morbidity and
mortality due to multiple organ dysfunction, especially acute lung injury (ALI) and acute …

Gram-negative bacterial sepsis remains a common, life-threatening event. The prognosis for
patients who develop sepsis-related complications, including the development of acute …

Sepsis and multiple organ failure continue to be significant problems among trauma, burn,
and the critically ill patient population. Thus, a number of laboratories have focused on …